BKC-2, a New BKC Variant Detected in MCR-9.1-Producing Enterobacter hormaechei subsp. xiangfangensis

Autor(es)

Martins, Willames M. B. S. ^{[1, 2]} ; Martins, Evelin R. ^[3] ; de Andrade, Leticia K. ^[3] ; Farzana, Refath ^[1] ; Walsh, Timothy R. ^[4] ; Toleman, Mark A. ^[1] ; Nogueira, Mara C. L. ^[3] ; Gales, Ana C. ^[2]

Afiliação do(s) autor(es)

^[1] Cardiff Univ, Div Infect & Immun, Dept Med Microbiol, Cardiff - Wales

^[2] Univ Fed Sao Paulo UNIFESP, Escola Paulista Med, Dept Internal Med, Div Infect Dis, Sao Paulo - Brazil

^[3] Fac Med Sao Jose do Rio Preto FAMERP, Ctr Invest Microrganismos, Sao Jose Do Rio Preto, SP - Brazil

^[4] Univ Oxford, Dept Zool, Oxford - England

• Tipo de documento: Artigo Científico
• Fonte: Antimicrobial Agents and Chemotherapy; v. 65, n. 3 MAR 2021.
• Citações Web of Science: 0

Resumo

We characterized a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An Enterobacter spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as Enterobacter hormaechei subsp. xiangfangensis strain ST451, showing an MDR profile and the presence of genes codifying the new beta-lactamase variants BKC-2 and ACT-84 and the mobile colistin resistance gene mcr-9.1. (AU)

• Processo FAPESP: 18/24431-4 - Investigação e caracterização de bacteriófagos com atividade lítica frente aos principais clones bacterianos epidêmicos em hospitais brasileiros
• Beneficiário: Willames Marcos Brasileiro da Silva Martins
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado