Plant-virus infection inhibitors: The great potential of Caryophyllales species

Autor(es)

Lembo Duarte, Ligia Maria ^[1] ; Vaz Alexandre, Maria Amelia ^[1] ; Rodrigues Chaves, Alexandre Levi ^[1] ; Alves Cursino dos Santos, Deborah Yara ^[2] ; Oliveira de Souza, Ana Claudia ^[3] ; Bernacci, Luis Carlos ^[3]

Afiliação do(s) autor(es)

^[1] Inst Biol, Lab Fitovirol & Fisiopatol, Av Conselheiro Rodrigues Alves 1252, BR-04014090 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Biociencias, Dept Bot, Lab Fitoquim, Sao Paulo - Brazil

^[3] Inst Agron Campinas, Ctr Recursos Genet Vegetais, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY; v. 113, JAN 2021.
• Citações Web of Science: 1

Resumo

Caryophyllales is one of the largest orders in eudicots and comprises 39 families with approximately 12,500 species. Although extracts from species of this order have been considered potential inhibitors of plant virus infection since the early 20th century, few species have actually been investigated. In this review, we present an exhaustive analysis of published papers that investigate this inhibitory effect, organized into one table with more than 100 species. In addition, the main hypotheses regarding the mode of action by which the compounds inhibit viral infection are discussed, providing several examples. The proteinaceous nature of antiviral proteins (AVP) produced by Caryophyllales, as well as the role of ribosome-inactivating proteins (RIPs) and pathogenesis-related proteins (PRs) as plant-defense inducers have received considerable attention. It is worth mentioning that data concerning the role of AVPs produced by species of Caryophyllales as signaling plant defense against viruses are scarce. Finally, this review proposes a model for the main mode of action hypotheses of viral infection inhibitors, and highlights the importance of surveying Caryophyllales species as an excellent strategy for controlling a broad spectrum of plant viruses from different taxonomic groups. (AU)

• Processo FAPESP: 16/25708-4 - Substâncias inibidoras de infecção viral provenientes de espécies nativas de Nyctaginaceae e Phytolaccaceae como indutores de defesa da planta
• Beneficiário: Lígia Maria Lembo Duarte
• Modalidade de apoio: Auxílio à Pesquisa - Regular