(-)-Hinokinin antimicrobial agents into functionalized mesoporous silica

Autor(es)

dos Santos Filho, Leodoro P. ^[1] ; Nascimento, de F. P. Maria P. ^[1] ; Marcal, Liziane ^[1] ; Ciuffi, Katia J. ^[1] ; Silva, Marcio L. A. e ^[1] ; Nassar, Eduardo J. ^[1] ; Rocha, Lucas A. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Franca, Ave Dr Armando Salles Oliveira, 201, Pq Univ, BR-14404600 Franca, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Sol-Gel Science and Technology; v. 98, n. 2 MAR 2021.
• Citações Web of Science: 0

Resumo

The sol-gel process emerges as an interesting strategy to obtain hybrid materials (organic-inorganic materials), it takes place under mild conditions and can produce nanoparticles with different shapes and sizes, leading to composite materials with multifunctional properties. In this paper will describe the synthesis and characterization of the mesoporous silica obtained by the sol-gel process as well as their potential applications as antimicrobial agents, biological markers, odontology, and others. Highly ordered mesoporous silica has gained attention from scientists because it exhibits large specific area and pore volume as well as low density. The preparation of mesoporous silica matrixes via the sol-gel process by using the surfactant cetyltrimethylammonium bromide and the copolymer Pluronic P-123 as structure-driving agents. The results revealed that samples V and VII behaved the most efficiently. Log(10) CFU/mL decreased by more than two digits for Candida albicans, Staphylococcus aureus, and Streptococcus mutans and was statistically significant for all the tested microorganisms. Therefore, this study demonstrated that the functionalized mesoporous silica is a viable antimicrobial agent when it is incorporated into dental acrylic resin. {[}GRAPHICS] . (AU)

• Processo FAPESP: 98/14956-7 - Investigação das atividades analgésica, anti-inflamatória e tripanocida de alguns derivados de cubebina obtidos por síntese parcial
• Beneficiário: Márcio Luís Andrade e Silva
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 19/02641-0 - 6th Nano Today Conference
• Beneficiário: Eduardo José Nassar
• Modalidade de apoio: Auxílio à Pesquisa - Reunião - Exterior
• Processo FAPESP: 15/20298-0 - Obtenção de matrizes luminescentes de LaNbO4:Ln (Ln = Dy, TM, er e Yb) pelo processo de pirólise de aerossol
• Beneficiário: Lucas Alonso Rocha
• Modalidade de apoio: Auxílio à Pesquisa - Regular