Mechanisms behind polyphagia in a pest insect: Responses of Spodoptera frugiperda (JE Smith) strains to preferential and alternative larval host plants assessed with gene regulatory networks

Autor(es)

Murad, Natalia Faraj ^[1] ; Silva-Brandao, Karina Lucas ^{[2, 1]} ; Brandao, Marcelo Mendes ^[1]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Ctr Biol Mol & Engn Genet CBMEG, Av Candido Rondon 400, BR-13083875 Campinas, SP - Brazil

^[2] Univ Fed ABC, Ctr Ciencias Nat & Humans, Av Estados 5001, BR-09210580 Santo Andre, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS; v. 1864, n. 3 MAR 2021.
• Citações Web of Science: 0

Resumo

A dataset of gene expression from Spodoptera frugiperda, a highly generalist pest moth, was used to understand how gene regulation is related to larval host plant preference. Transcriptomic data of corn and rice strains of S. frugiperda larvae, reared on different diets, were analysed with three different approaches of gene network inference, namely co-expression, weighted co-expression and Bayesian networks, since each methodology provides a different visualization of the data. Using these approaches, it was possible to identify two loosely interconnected co-expression networks, one of them responsible for fast response to herbivory and anti-herbivory mechanisms and the other related to housekeeping genes, which present slower response to environmental variations. Integrating different levels of information such as gene expression patterns, gene assembly, transcriptomics, relationship among genes and phenotypes, functional relationships, among other information, enabled a wider visualization of S. frugiperda response to diet stimuli. The biological properties in the proposed networks are here described and discussed, as well as patterns of gene expression related to larval performance attributes. (AU)

• Processo FAPESP: 12/16266-7 - Genômica populacional: uma nova abordagem para estudos de especiação em insetos devido ao uso de hospedeiros aplicada ao desenvolvimento de estratégias sustentáveis de MIP
• Beneficiário: Karina Lucas da Silva-Brandão
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 11/00417-3 - Biologia de sistemas aplicada a agricultura: análise de transcriptomas e interactomas
• Beneficiário: Marcelo Mendes Brandao
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores