Frontal Hemodynamic Response During Step Initiation Under Cognitive Conflict in Older and Young Healthy People

Autor(es)

Coelho, Daniel Boari ^[1] ; Bazan, Paulo Rodrigo ^{[2, 3]} ; Zimeo Morais, Guilherme Augusto ^[3] ; Balardin, Joana Bisol ^[3] ; Batista, Alana Xavier ^[2] ; Neves de Oliveira, Claudia Eunice ^[1] ; Los Angeles, Emanuele ^[1] ; Bernardo, Claudionor ^[1] ; Sato, Joao Ricardo ^[4] ; de Lima-Pardini, Andrea C. ^[5]

Afiliação do(s) autor(es)

^[1] Fed Univ ABC, Biomed Engn, Sao Bernardo Do Campo, SP - Brazil

^[2] Univ Sao Paulo, Fac Med, Dept Radiol, Sao Paulo - Brazil

^[3] Hosp Israelita Albert Einstein, Big Data Analyt, Sao Paulo - Brazil

^[4] Univ Fed ABC, Ctr Math Comp & Cognit, Sao Bernardo Do Campo, SP - Brazil

^[5] Queens Univ, Ctr Neurosci Studies, Lab Integrat Motor Behav, Kingston, ON - Canada

• Tipo de documento: Artigo Científico
• Fonte: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES; v. 76, n. 2, p. 216-223, FEB 2021.
• Citações Web of Science: 0

Resumo

Gait initiation is a daily challenge even for healthy individuals as it requires the timely coupling between the automatic anticipatory postural adjustment (APA) and the voluntary step according to the context. Modulation of this motor event has been thought to involve higher level brain control, including cognitive inhibitory circuitries. Despite the known participation of the supplementary motor area (SMA) in the modulation of some parameters of APA, the participation of areas controlling inhibition during gait initiation still needs to be investigated. In this study, the hemodynamic responses of the SMA and dorsolateral prefrontal cortex (DLPFC) were assessed using functional near-infrared spectroscopy (fNIRS) during a gait initiation task under cognitive conflict to select the foot to step (congruent {[}CON] and incongruent {[}INC] conditions). The older group (OG) showed worse inhibitory control than the young group (YG) along with more impairments in APA parameters. OG also had a lower amplitude of hemodynamic responses in both areas than YG in the INC. The INC increased the correlation between SMA and DLPFC only in the YG. Aging seems to impair the interaction between the hemodynamic responses of SMA and DLPFC, which influences APA performance in gait initiation under cognitive conflict. (AU)

• Processo FAPESP: 15/14810-0 - Biomecânica e aspectos funcionais do sistema musculoesquelético de corredores: efeito crônico de exercícios terapêuticos e do envelhecimento
• Beneficiário: Isabel de Camargo Neves Sacco
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 19/06604-1 - Aquisição de dados na avaliação clínica e modelagem biomecânica com inovações tecnológicas buscando a restauração de movimentos e o desempenho esportivo para pessoas com deficiências
• Beneficiário: Claudiane Arakaki Fukuchi
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 14/13502-7 - Efeito da velocidade de locomoção sobre o padrão de movimento na marcha de adultos e idosos: estudo experimental, simulação computacional e criação de base de dados
• Beneficiário: Claudiane Arakaki Fukuchi
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto