hytic acid accumulation in plants: Biosynthesis pathway regulation and role in human die

Autor(es)

Silva, Vinicius Martins ^[1] ; Putti, Fernando Ferrari ^[2] ; White, Philip J. ^[3] ; dos Reis, Andre Rodrigues ^[2]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, BR-14884900 Jaboticabal, SP - Brazil

^[2] Sao Paulo State Univ UNESP, BR-17602496 Tupa, SP - Brazil

^[3] James Hutton Inst, Dundee DD2 5DA - Scotland

• Tipo de documento: Artigo de Revisão
• Fonte: Plant Physiology and Biochemistry; v. 164, p. 132-146, JUL 2021.
• Citações Web of Science: 1

Resumo

Phytate or phytic acid (PA), is a phosphorus (P) containing compound generated by the stepwise phosphorylation of myo-inositol. It forms complexes with some nutrient cations, such as Ca, Fe and Zn, compromising their absorption and thus acting as an anti-nutrient in the digestive tract of humans and monogastric animals. Conversely, PAs are an important form of P storage in seeds, making up to 90% of total seed P. Phytates also play a role in germination and are related to the synthesis of abscisic acid and gibberellins, the hormones involved in seed germination. Decreasing PA content in plants is desirable for human dietary. Therefore, low phytic acid (lpa) mutants might present some negative pleiotropic effects, which could impair germination and seed viability. In the present study, we review current knowledge of the genes encoding enzymes that function in different stages of PA synthesis, from the first phosphorylation of myo-inositol to PA transport into seed reserve tissues, and the application of this knowledge to reduce PA concentrations in edible crops to enhance human diet. Finally, phylogenetic data for PA concentrations in different plant families and distributed across several countries under different environmental conditions are compiled. The results of the present study help explain the importance of PA accumulation in different plant families and the distribution of PA accumulation in different foods. (AU)

• Processo FAPESP: 16/19773-8 - Caracterização da variação genotípica e biofortificação agronômica do feijão-caupi com selênio para obtenção de grãos de alta qualidade nutricional e baixa concentração de fitatos
• Beneficiário: Vinicius Martins Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 20/12218-4 - Interação entre selênio e enxofre no metabolismo de aminoácidos e flavonoides e sua relação com a nodulação de leguminosas
• Beneficiário: Vinicius Martins Silva
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
• Processo FAPESP: 18/18936-6 - Biofortificação agronômica com selênio e zinco e interação sulfato x selenato na assimilação de selênio na cultura do feijão-caupi
• Beneficiário: Vinicius Martins Silva
• Modalidade de apoio: Bolsas no Brasil - Doutorado