Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Muscle-strengthening activities and cancer incidence and mortality: a systematic review and meta-analysis of observational studies

Texto completo
Autor(es):
Nascimento, Wilson [1] ; Ferrari, Gerson [2] ; Martins, Camila Bertini [1] ; Rey-Lopez, Juan Pablo [3, 4] ; Izquierdo, Mikel [5] ; Lee, Dong Hoon [6] ; Giovannucci, Edward L. [7, 8, 6, 9] ; Rezende, Leandro F. M. [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Fed Sao Paulo, Escola Paulista Med, Dept Med Prevent, Sao Paulo, SP - Brazil
[2] Univ Santiago de Chile USACH, Escuela Ciencias Act Fis Deporte & Salud, Santiago - Chile
[3] Int Univ Valencia VIU, Fac Hlth Sci, Valencia - Spain
[4] Catholic Univ San Antonio Murcia, Fac Sport, Murcia - Spain
[5] Univ Publ Navarra UPNA, Navarra Hosp Complex NHC, Navarrabiomed, IdiSNA, Pamplona - Spain
[6] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA - USA
[7] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA - USA
[8] Harvard Med Sch, Boston, MA 02115 - USA
[9] Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 - USA
Número total de Afiliações: 9
Tipo de documento: Artigo de Revisão
Fonte: International Journal of Behavioral Nutrition and Physical Activity; v. 18, n. 1 MAY 29 2021.
Citações Web of Science: 0
Resumo

Background Physical activity has been associated with reduced risk of seven types of cancer. It remains unclear, however, whether muscle-strengthening activities also reduce cancer incidence and mortality. Methods PubMed, Embase, Web of Science and Scopus were searched from inception to March 2020. Summary hazard ratio (HR) and 95% confidence intervals (CI) were estimated using random-effects models. Results Twelve studies (11 cohorts; 1 case-control), 6 to 25 years of follow-up, including 1,297,620 participants, 32,196 cases and 31,939 deaths, met inclusion criteria. Muscle-strengthening activities were associated with a 26% lower incidence of kidney cancer (HR for high vs low levels of muscle-strengthening activities: 0.74; 95% CI 0.56 to 0.98; I-2 0%; 2 studies), but not with incidence of other 12 types of cancer. Muscle-strengthening activities were associated with lower total cancer mortality: HRs for high vs low levels of muscle-strengthening activities was 0.87 (95% CI 0.73 to 1.02; I-2 58%; 6 studies); and HR for >= 2 times/week vs < 2 times/week of muscle-strengthening activities was 0.81 (95% CI 0.74 to 0.87; I-2 0%; 4 studies). Regarding the weekly duration of muscle-strengthening activities, HR for total cancer mortality were 0.91 (95% CI 0.82 to 1.01; I-2 0%; 2 studies) for 1-59 min/week and 0.98 (95% CI 0.89 to 1.07; I-2 0%) for >= 60 min/week vs none. Combined muscle-strengthening and aerobic activities (vs none) were associated with a 28% lower total cancer mortality (HR 0.72; 95% CI 0.53 to 0.98; I-2 85%; 3 studies). Conclusions Muscle-strengthening activities were associated with reduced incidence of kidney cancer and total cancer mortality. Combined muscle-strengthening and aerobic activities may provide a greater reduction in total cancer mortality. (AU)

Processo FAPESP: 19/26326-6 - Exercício de força muscular e prevenção de câncer: uma revisão sistemática e meta-análise
Beneficiário:Wilson Guilherme Aparecido Nascimento
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica