Relationship between Mediterranean Diet Adherence and Saliva Composition

Autor(es)

Louro, Teresa ^[1] ; Simoes, Carla ^[1] ; Penetra, Maria Joao ^[2] ; Carreira, Laura ^[1] ; Castelo, Paula Midori ^[3] ; Luis, Henrique ^{[4, 5]} ; Moreira, Pedro ^[6] ; Lamy, Elsa ^[1]

Afiliação do(s) autor(es)

^[1] Univ Evora, Med Mediterranean Inst Agr, Inst Adv Studies & Res IIFA, IIFA Inst Invest & Formacao Avancada, P-7002556 Evora - Portugal

^[2] Univ Evora, Dept Biol, P-7002556 Evora - Portugal

^[3] Univ Fed Sao Paulo UNIFESP, Dept Pharmaceut Sci, BR-09972270 Diadema - Brazil

^[4] Univ Lisbon, Fac Med Dentaria, Unidade Invest Ciencias Orais & Biomed UICOB, P-1600277 Lisbon - Portugal

^[5] Politecn Leiria, Ctr Innovat Care & Hlth Technol CiThecCare, P-2411901 Leiria - Portugal

^[6] Univ Porto, Fac Ciencias Nutr & Aliment, P-4150180 Porto - Portugal

• Tipo de documento: Artigo Científico
• Fonte: NUTRIENTS; v. 13, n. 4 APR 2021.
• Citações Web of Science: 0

Resumo

Dietary polyphenol exposure is known to change protein saliva composition in rodents, but less is known in humans. The present study aimed to assess the relationship between saliva protein composition and adherence to Mediterranean Diet (MD) and polyphenol intake levels. Participants were assessed for their dietary habits, which were converted in Mediterranean adherence level, according to Mediterranean Diet Adherence Score (MEDAS) score. Total polyphenol and total flavanol intakes were extrapolated from dietary data, using Phenol explorer database. Whole saliva was collected, and proteins were separated by SDS-PAGE. Salivary S-type cystatins were highly expressed in the group with medium adherence to MD, being positively correlated with wine intake in overweight individuals. The association between salivary amylase and MD adherence also depended on Body Mass Index (BMI), with a positive association only in normal weight individuals. Polyphenol intake was positively associated with S-type cystatins levels, particularly when flavanols were considered separately. These results show that saliva relationship with MD adherence depend on BMI, suggesting that normal weight and overweight individuals may have different salivary responses to diet. Moreover, these results reinforce the link between saliva and dietary polyphenols (flavanols) levels, leading to the hypothesis that salivary proteome can have a role in polyphenol-rich foods acceptance. (AU)

• Processo FAPESP: 17/26400-6 - Impacto da gastroplastia na composição salivar e na citomorfologia da mucosa oral: acompanhamento de três e seis meses
• Beneficiário: Paula Midori Castelo Ferrua
• Modalidade de apoio: Auxílio à Pesquisa - Regular