| Texto completo | |
| Autor(es): |
De Mattos, Luiz Carlos
[1]
;
Ferreira, Ana Iara Costa
[1]
;
de Oliveira, Karina Younan
[1]
;
Nakashima, Fabiana
[1]
;
Brandao, Cinara Cassia
[1, 2]
Número total de Autores: 5
|
| Afiliação do(s) autor(es): | [1] Fac Med FAMERP, Dept Mol Biol, Immunogenet Lab, Sao Jose Do Rio Preto - Brazil
[2] Fac Med FAMERP, Dept Mol Biol, FAMERP Toxoplasma Res Grp, Sao Jose Do Rio Preto - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY; v. 11, JUN 18 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues. The combined action of these glycosyltransferases strongly influences cell, tissue, mucosa, and exocrine secretion carbohydrate phenotypes, including those serving as habitat for mutualistic and pathogenic microorganisms. A set of reports investigated associations between Toxoplasma gondii infection and the ABO histo-blood group system, but the results are contradictory. As T. gondii uses the gastrointestinal tract as a route for infection, and in this organ, the expression of ABO, Lewis, and Secretor histo-blood group carbohydrates occurs, it is reasonable to suppose some biological relationship between them. This text reviewed association studies published in recent decades focusing on the potential contribution of the ABO, Lewis, and Secretor histo-blood group carbohydrates and infection by T. gondii. (AU) | |
| Processo FAPESP: | 09/17540-2 - Sistemas histo-sanguíneos como fatores de risco para a toxoplasmose ocular |
| Beneficiário: | Luiz Carlos de Mattos |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 12/07716-9 - Investigação sorológica e molecular de Toxoplasma gondii em doadores de sangue |
| Beneficiário: | Luiz Carlos de Mattos |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |