| Full text | |
| Author(s): |
De Mattos, Luiz Carlos
[1]
;
Ferreira, Ana Iara Costa
[1]
;
de Oliveira, Karina Younan
[1]
;
Nakashima, Fabiana
[1]
;
Brandao, Cinara Cassia
[1, 2]
Total Authors: 5
|
| Affiliation: | [1] Fac Med FAMERP, Dept Mol Biol, Immunogenet Lab, Sao Jose Do Rio Preto - Brazil
[2] Fac Med FAMERP, Dept Mol Biol, FAMERP Toxoplasma Res Grp, Sao Jose Do Rio Preto - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY; v. 11, JUN 18 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues. The combined action of these glycosyltransferases strongly influences cell, tissue, mucosa, and exocrine secretion carbohydrate phenotypes, including those serving as habitat for mutualistic and pathogenic microorganisms. A set of reports investigated associations between Toxoplasma gondii infection and the ABO histo-blood group system, but the results are contradictory. As T. gondii uses the gastrointestinal tract as a route for infection, and in this organ, the expression of ABO, Lewis, and Secretor histo-blood group carbohydrates occurs, it is reasonable to suppose some biological relationship between them. This text reviewed association studies published in recent decades focusing on the potential contribution of the ABO, Lewis, and Secretor histo-blood group carbohydrates and infection by T. gondii. (AU) | |
| FAPESP's process: | 09/17540-2 - Histo blood groups like risk factor for ocular toxoplasmosis |
| Grantee: | Luiz Carlos de Mattos |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/07716-9 - Serological and molecular investigation of Toxoplasma gondii in blood donors |
| Grantee: | Luiz Carlos de Mattos |
| Support Opportunities: | Regular Research Grants |