Jaboticaba, a Brazilian jewel, source of antioxidant and wound healing promoter

Autor(es)

Cefali, Leticia Caramori ^[1] ; Franco, Julia Gomes ^[2] ; Nicolini, Giulia Ferreira ^[2] ; dos Santos, Erica Mendes ^[2] ; Masquetti Fava, Ana Laura ^[3] ; Figueiredo, Mariana Cecchetto ^[3] ; Ataide, Janaina Artem ^[2] ; Foglio, Mary Ann ^[2] ; Mazzola, Priscila Gava ^[2]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Inst Biol, R Monteiro Lobato 255, BR-13083862 Campinas, SP - Brazil

^[2] Univ Campinas UNICAMP, Fac Pharmaceut Sci, Rua Candido Portinari 200, BR-13083871 Campinas, SP - Brazil

^[3] Univ Campinas UNICAMP, Sch Med Sci, R Sergio Buarque Holanda 250, BR-13083859 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SUSTAINABLE CHEMISTRY AND PHARMACY; v. 20, MAY 2021.
• Citações Web of Science: 0

Resumo

This study aims to evaluate properties as antioxidant activity, solar protection factor (SPF) and wound healing ability of jaboticaba peel's extract by in vitro methods. Jaboticaba peels were removed, dried, and then subjected to extraction method using ethanol. The extract was in vitro evaluated for preliminary studies about SPF, antioxidant activity and wound healing assay. Thereafter the extract was incorporated in an oil-in-water emulsion (phytocosmetic). The phytocosmetic was submitted to stability study and in vitro SPF evaluation. The extract's showed purple color with in vitro SPF of 24.86, stimulated keratinocytes migration after 9 h of exposition and presented antioxidant activity. The incorporation of the extract gave the phytocosmetic formulation a light pink shade with an in vitro SPF of 19.00. Under stress conditions, the formulation was stable, especially when stored in low temperatures. Jaboticaba peel extract promoted wound healing in vitro presenting SPF and antioxidant activity. Final phytocosmetic formulation was stable when stored protect from light and heat, indicating that Jaboticaba extract can be used to develop products to protect skin against aging and sun exposure. (AU)

• Processo FAPESP: 15/25533-7 - Desenvolvimento e avaliação do fator de proteção solar de emulsão contendo extrato rico em flavonóides
• Beneficiário: Leticia Caramori Cefali
• Modalidade de apoio: Bolsas no Brasil - Doutorado