icroorganisms as bioabatement agents in biomass to bioproducts application

Autor(es)

Sodre, Victoria ^{[1, 2]} ; Vilela, Nathalia ^{[1, 2]} ; Tramontina, Robson ^{[1, 3, 4]} ; Squina, Fabio Marcio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sorocaba UNISO, Programa Proc Tecnol & Ambientais, Sorocaba, SP - Brazil

^[2] Univ Estadual Campinas, Inst Biol IB, Dept Bioquim & Biol Tecidual DBBT, UNICAMP, Campinas, SP - Brazil

^[3] Univ Estadual Campinas, Fac Engn Alimentos FEA, UNICAMP, Campinas, SP - Brazil

^[4] Univ Estadual Campinas, Inst Biol IB, Programa Posgrad Biociencias & Tecnol Prod Bioat, UNICAMP, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BIOMASS & BIOENERGY; v. 151, AUG 2021.
• Citações Web of Science: 1

Resumo

The biorefinery concept for production of biofuels and chemicals, based on lignocellulosic biomass, represents an attractive and sustainable alternative to fossil fuel-based refineries. The inherent recalcitrance of lignocellulosic biomass requires a physical-chemical pretreatment prior to the biocatalytic conversion of monomeric constituents of plant cell walls into bioproducts. However, the pretreatment step often generates fermentation inhibitors, such as furfural, 5-hydroxymethylfurfural, aliphatic acids, and phenolic acids and aldehydes. Thus, a detoxification step prior, or simultaneous to microbial fermentation, is of prime importance to improve product yields. Among detoxification strategies, biological detoxification, also known as bioabatement, arises as an ecofriendlier, milder, and cheaper alternative to physical-chemical detoxification methods. In the present review, the state-of-the-art and recent advances in the field of microbial detoxification of lignocellulosic hydrolysates are thoroughly presented. After introducing the general aspects of the theme, including the generation of inhibitory compounds from lignocellulosic biomass pretreatment and their effects on enzymatic hydrolysis and cell physiology, in-depth analyses of biological detoxification strategies reported in the literature are presented for the following microbial groups: filamentous fungi, non-Saccharomyces yeasts, bacteria, and Saccharomyces cerevisiae. Furthermore, the advantages and disadvantages of microbial detoxification are discussed, and the main challenges currently faced by researchers in the field are addressed. (AU)

• Processo FAPESP: 16/07926-4 - Novas estratégias integrativas através de uma aldoketo redutase do cupim Coptotermes gestroi para sacarificação, detoxificação e fermentação de lignocelulose visando a produção de bioetanol
• Beneficiário: Robson Tramontina
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 18/18101-1 - Desenvolvimento do sistema CRISPR/Cas9 em Rhodococcus jostii RHA1 para produção de químicos de alto valor a partir de correntes de lignina
• Beneficiário: Victoria Ramos Sodré de Castro
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 15/50590-4 - Valorização da lignina em plantas de etanol celulósico: a conversão biocatalítica via ácido ferúlico a produtos químicos de alto valor
• Beneficiário: Fábio Márcio Squina
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Temático
• Processo FAPESP: 17/08166-6 - Desenvolvimento de uma levedura capaz de converter material lignocelulósico em ácido ferúlico
• Beneficiário: Nathália Vilela
• Modalidade de apoio: Bolsas no Brasil - Doutorado