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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Cardiopulmonary alterations by ultrasound in a patient with uncomplicated mixed malaria infection: a case report from the Amazon Basin

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Autor(es):
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Wegener, Alma [1, 2] ; Lima, Karine O. [1] ; Holm, Anna E. [1, 2] ; Gomes, Laura C. [3] ; Matos, Luan O. [1] ; Vieira, Isabelle V. M. [1] ; Souza, Rodrigo Medeiros [1] ; Farias Marinho, Claudio Romero [3] ; Vestergaard, Lasse S. [4] ; Biering-Sorensen, Tor [2, 5] ; Silvestre, Odilson M. [6] ; Brainin, Philip [1, 2]
Número total de Autores: 12
Afiliação do(s) autor(es):
[1] Univ Fed Acre, Multidisciplinary Ctr, Campus Floresta, Cruzeiro Do Sul, Acre - Brazil
[2] Univ Copenhagen, Herlev & Gentofte Hosp, Dept Cardiol, Cardiovasc Noninvas Imaging Res Lab, Hosp Vej 8, Post 835, DK-2900 Copenhagen - Denmark
[3] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, Sao Paulo - Brazil
[4] Statens Serum Inst, Natl Malaria Reference Lab, Dept Bacteria Parasites & Fungi, Copenhagen - Denmark
[5] Univ Copenhagen, Fac Biomed Sci, Copenhagen - Denmark
[6] Univ Fed Acre, Hlth & Sport Sci Ctr, Rio Branco, Acre - Brazil
Número total de Afiliações: 6
Tipo de documento: Artigo Científico
Fonte: Malaria Journal; v. 20, n. 1 JUL 28 2021.
Citações Web of Science: 0
Resumo

BackgroundInformation on cardiopulmonary complications in clinical malaria is sparse and diagnosis may be difficult in resource-limited areas due to lack of proper diagnostic tools and access to medical care. A case of pericardial effusion and pulmonary alterations assessed by ultrasound in a patient with uncomplicated mixed malaria infection is described.Case presentationA previously healthy 23-year-old male from the Amazon Basin was diagnosed with mixed infection of Plasmodium vivax and Plasmodium falciparum by peripheral blood smear. The patient presented with mild malaria symptoms without signs of severe malaria, but reported moderate chest pain and shortness of breath. Laboratory analyses revealed thrombocytopenia and anemia. The electrocardiogram had PR depressions and bedside ultrasound of the cardiopulmonary system showed pericardial effusion (18 mm) accompanied by multiple B-lines in the lungs, identified as vertical artifacts extending from the pleural line. Cardiac biomarkers were normal. The patient was treated according to national guidelines for malaria and suspected pericarditis, respectively. At follow-up on day 5, the pericardial effusion (9mm) and B-lines had markedly decreased. By day 21 the patient was asymptomatic, had completed the treatment, and the electrocardiogram and ultrasound findings had normalized.ConclusionsThis case report highlight the usefulness of bedside ultrasound to identify cardiopulmonary involvement in patients with uncomplicated malaria and relevant symptoms. (AU)

Processo FAPESP: 20/06747-4 - Estudo da resposta imune humoral nas infecções recorrentes por Plasmodium vivax em gestantes da região amazônica
Beneficiário:Cláudio Romero Farias Marinho
Modalidade de apoio: Auxílio à Pesquisa - Regular