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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cardiopulmonary alterations by ultrasound in a patient with uncomplicated mixed malaria infection: a case report from the Amazon Basin

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Author(s):
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Wegener, Alma [1, 2] ; Lima, Karine O. [1] ; Holm, Anna E. [1, 2] ; Gomes, Laura C. [3] ; Matos, Luan O. [1] ; Vieira, Isabelle V. M. [1] ; Souza, Rodrigo Medeiros [1] ; Farias Marinho, Claudio Romero [3] ; Vestergaard, Lasse S. [4] ; Biering-Sorensen, Tor [2, 5] ; Silvestre, Odilson M. [6] ; Brainin, Philip [1, 2]
Total Authors: 12
Affiliation:
[1] Univ Fed Acre, Multidisciplinary Ctr, Campus Floresta, Cruzeiro Do Sul, Acre - Brazil
[2] Univ Copenhagen, Herlev & Gentofte Hosp, Dept Cardiol, Cardiovasc Noninvas Imaging Res Lab, Hosp Vej 8, Post 835, DK-2900 Copenhagen - Denmark
[3] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, Sao Paulo - Brazil
[4] Statens Serum Inst, Natl Malaria Reference Lab, Dept Bacteria Parasites & Fungi, Copenhagen - Denmark
[5] Univ Copenhagen, Fac Biomed Sci, Copenhagen - Denmark
[6] Univ Fed Acre, Hlth & Sport Sci Ctr, Rio Branco, Acre - Brazil
Total Affiliations: 6
Document type: Journal article
Source: Malaria Journal; v. 20, n. 1 JUL 28 2021.
Web of Science Citations: 0
Abstract

BackgroundInformation on cardiopulmonary complications in clinical malaria is sparse and diagnosis may be difficult in resource-limited areas due to lack of proper diagnostic tools and access to medical care. A case of pericardial effusion and pulmonary alterations assessed by ultrasound in a patient with uncomplicated mixed malaria infection is described.Case presentationA previously healthy 23-year-old male from the Amazon Basin was diagnosed with mixed infection of Plasmodium vivax and Plasmodium falciparum by peripheral blood smear. The patient presented with mild malaria symptoms without signs of severe malaria, but reported moderate chest pain and shortness of breath. Laboratory analyses revealed thrombocytopenia and anemia. The electrocardiogram had PR depressions and bedside ultrasound of the cardiopulmonary system showed pericardial effusion (18 mm) accompanied by multiple B-lines in the lungs, identified as vertical artifacts extending from the pleural line. Cardiac biomarkers were normal. The patient was treated according to national guidelines for malaria and suspected pericarditis, respectively. At follow-up on day 5, the pericardial effusion (9mm) and B-lines had markedly decreased. By day 21 the patient was asymptomatic, had completed the treatment, and the electrocardiogram and ultrasound findings had normalized.ConclusionsThis case report highlight the usefulness of bedside ultrasound to identify cardiopulmonary involvement in patients with uncomplicated malaria and relevant symptoms. (AU)

FAPESP's process: 20/06747-4 - Study of the humoral immune response in recurrent infections by Plasmodium vivax in pregnant women from Amazon region
Grantee:Cláudio Romero Farias Marinho
Support Opportunities: Regular Research Grants