An Overview on Topical Administration of Carotenoids and Coenzyme Q10 Loaded in Lipid Nanoparticles

Autor(es)

de Souza Guedes, Luciana ^[1] ; Martinez, Renata Miliani ^[1] ; Bou-Chacra, Nadia A. ^[1] ; Velasco, Maria Valeria Robles ^[1] ; Rosado, Catarina ^[2] ; Baby, Andre Rolim ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Pharm, BR-05508900 Sao Paulo - Brazil

^[2] Univ Lusofonas, Res Ctr Biosci & Hlth Technol, CBIOS, P-1749024 Lisbon - Portugal

• Tipo de documento: Artigo de Revisão
• Fonte: ANTIOXIDANTS; v. 10, n. 7 JUL 2021.
• Citações Web of Science: 1

Resumo

Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are also found in human skin. These bioactive compounds have been the focus of considerable research due to their antioxidant, anti-inflammatory, and photoprotective properties. In this review, the current state of the art in the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to improve their bioavailability, chemical stability, and skin absorption is discussed. Additionally, the main findings are highlighted on the cytotoxic and photoprotective effects of these systems in the skin. (AU)

• Processo FAPESP: 19/16169-0 - Estabelecimento ex vivo e in vivo de novas propriedades quimiopreventivas de filtros solares
• Beneficiário: André Rolim Baby
• Modalidade de apoio: Auxílio à Pesquisa - Regular