Adiponectin Concentration and Chronic Stroke Individuals, Associations with Body Composition, Physical Activity Levels and Lipid Profile: A Cross-Sectional Explorative Study

Autor(es)

Garcia-Salazar, Luisa Fernanda ^{[1, 2]} ; Ribeiro, Jean Alex Matos ^[1] ; Saade-Pacheco, Cassia Regina ^{[1, 3]} ; Mattiello, Stela Marcia ^[1] ; Catai, Aparecida Maria ^[1] ; Garcia-Araujo, Adriana Sanches ^[1] ; Russo, Thiago Luiz ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Carlos, Dept Phys Therapy, Sao Carlos - Brazil

^[2] Univ Rosario, Sch Med & Hlth Sci, Rehabil Sci Res Grp, Phys Therapy Program, Bogota - Colombia

^[3] Educ Fdn Municipal Assis, Municipal Inst Higher Educ Assis, Assis - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES; v. 30, n. 10 OCT 2021.
• Citações Web of Science: 0

Resumo

Objective: Higher adiponectin concentration has been associated with the presence of sarcopenia in individuals with cardiovascular diseases. Post-stroke individuals presented higher adiponectin concentrations than non-stroke ones. However, no previous study has investigated the association between the adiponectin concentration and skeletal muscle mass in post-stroke individuals. On the other hand, higher adiponectin concentration has been associated with a more favorable lipid profile and the physical activity level might regulate adiponectin concentration. These associations have not been studied in this population. Thus, the main objective of this study was to determine whether the adiponectin concentration is associated with: (1) body composition; (2) lipid profile; and (3) physical activity level in chronic post-stroke individuals. Materials and Methods: This study was a correlational, crosssectional exploratory study. Data on body composition and lipid profile were collected using a bioelectrical impedance analyzer (InBody (R) 720) and an automated method analyzer (CELL-DYN Ruby), respectively. The physical activity level was measured by the StepWatch (R) Activity Monitor and the serum adiponectin concentration was analyzed using an enzyme-linked immunosorbent assay kit. Correlation analyses were made using Spearman's rank correlation coefficient (r(s)). Results: Twenty-one post-stroke participants took part in the study. The adiponectin concentration was associated with the following: skeletal muscle mass (r(s) = -0.78), skeletal muscle mass index (r(s) = -0.75) and high-density lipoprotein (r(s) = 0.43). Conclusions: A greater adiponectin concentration is associated with a lower skeletal muscle mass and a higher high-density lipoprotein level in chronic post-stroke individuals, but not with physical activity levels. (AU)

• Processo FAPESP: 17/13655-6 - Sedentarismo e disfunção arterial em indivíduos pós-acidente vascular cerebral crônico
• Beneficiário: Thiago Luiz de Russo
• Modalidade de apoio: Auxílio à Pesquisa - Regular