Fish genomics and its impact on fundamental and applied research of vertebrate biology

Autor(es)

Ahmad, Syed Farhan ^{[1, 2, 3]} ; Jehangir, Maryam ^[1] ; Srikulnath, Kornsorn ^{[2, 3]} ; Martins, Cesar ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, Inst Biosci Botucatu, Dept Struct & Funct Biol, BR-18618689 Botucatu, SP - Brazil

^[2] Kasetsart Univ, Lab Anim Cytogenet & Comparat Genom ACCG, Dept Genet, Fac Sci, 50 Ngamwongwan, Bangkok 10900 - Thailand

^[3] Kasetsart Univ, Special Res Unit Wildlife Genom SRUWG, Dept Forest Biol, Fac Forestry, 50 Ngamwongwan, Bangkok 10900 - Thailand

• Tipo de documento: Artigo de Revisão
• Fonte: Reviews in Fish Biology and Fisheries; OCT 2021.
• Citações Web of Science: 0

Resumo

The living fishes span a unique and interesting set of animals because of their vast diversity, morphology, ecology, genetics and genomics, and higher importance to biology, economy and culture. During the past decade, the remarkable increase in fish genome sequencing has revolutionized comparative and evolutionary genomics, with the outcome of stimulating insights into vertebrate genome biology. Fish genomics has been transformed rapidly, with the availability of high-quality chromosome level genome assemblies and large collections of sequencing datasets, which are roadmaps for striking discoveries. Landmark achievements are being made; such as the accomplishment of fully assembled lungfish genome which is biggest genome ever sequenced. Here, we highlight current developments in vertebrate's comparative genomics and discuss how fish genomes could be considered as vital resources for genomic studies. We present a recent overview of genomics data, address different approaches applicable to comparative genomics analyses, and illustrate these comparisons to better understand the complex mechanisms under the vertebrate genomes. We also summarize the applications in chromosomes research and cytogenomics. (AU)

• Processo FAPESP: 15/16661-1 - Cromossomos sexuais, cromossomos B e seus enigmas: sistemas modelo para estudos de evolução cromossômica e genômica
• Beneficiário: César Martins
• Modalidade de apoio: Auxílio à Pesquisa - Temático