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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Visual neuroscience methods for marmosets: efficient receptive field mapping and head-free eye tracking

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Autor(es):
Jendritza, Patrick [1, 2] ; Klein, Frederike J. [2] ; Rohenkohl, Gustavo [3, 2] ; Fries, Pascal [4, 2]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Int Max Planck Res Sch Neural Circuits, Frankfurt - Germany
[2] Ernst Strungmann Inst ESI, Neurosci Cooperat Max Planck Soc, Deutschordenstr 46, D-60528 Frankfurt - Germany
[3] Univ Sao Paulo, Inst Biosci, Dept Physiol, Sao Paulo - Brazil
[4] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen - Netherlands
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: ENEURO; v. 8, n. 3 MAY-JUN 2021.
Citações Web of Science: 1
Resumo

The marmoset has emerged as a promising primate model system, in particular for visual neuroscience. Many common experimental paradigms rely on head fixation and an extended period of eye fixation during the presentation of salient visual stimuli. Both of these behavioral requirements can be challenging for marmosets. Here, we present two methodological developments, each addressing one of these difficulties. First, we show that it is possible to use a standard eye tracking system without head fixation to assess visual behavior in the marmoset. Eye tracking quality from head-free animals is sufficient to obtain precise psychometric functions from a visual acuity task. Secondly, we introduce a novel method for efficient receptive field mapping that does not rely on moving stimuli but uses fast flashing annuli and wedges. We present data recorded during head-fixation in areas V1 and V6 and show that receptive field locations are readily obtained within a short period of recording time. Thus, the methodological advancements presented in this work will contribute to establish the marmoset as a valuable model in neuroscience. (AU)

Processo FAPESP: 17/10429-5 - Conectividade neural durante o comportamento visual ativo
Beneficiário:Gustavo Rohenkohl
Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
Processo FAPESP: 18/16635-9 - Conectividade neural durante o comportamento visual ativo
Beneficiário:Gustavo Rohenkohl
Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores