Draft genome sequence of the cyanobacterium Sphaerospermopsis aphanizomenoides BCCUSP55 from the Brazilian semiarid region reveals potential for anti-cancer applications

Autor(es)

Lorenzi, Adriana Sturion ^{[1, 2]} ; Bonatelli, Maria Leticia ^[3] ; Varani, Alessandro M. ^[4] ; Quecine, Maria Carolina ^[3] ; Bittencourt-Oliveira, Maria do Carmo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Luiz de Queiroz Coll Agr, Dept Biol Sci, Piracicaba, SP - Brazil

^[2] Univ Brasilia UnB, Inst Biol Sci, Dept Cellular Biol, Brasilia, DF - Brazil

^[3] Univ Sao Paulo, Luiz de Queiroz Coll Agr, Dept Genet, Piracicaba, SP - Brazil

^[4] Sao Paulo State Univ, Sch Agr & Vet Sci, Jaboticabal, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Archives of Microbiology; v. 204, n. 1 JAN 2022.
• Citações Web of Science: 0

Resumo

Sphaerospermopsis aphanizomenoides is a filamentous nitrogen-fixing and bloom-forming cyanobacterium, which biomass can fertilize natural water with nutrients, especially through nitrogen fixation. The Sphaerospermopsis aphanizomenoides strain BCCUSP55 was previously isolated from a water supply reservoir in the Brazilian semiarid region, and its draft genome assembly coupled with the gene contents are reported here. The obtained BCCUSP55 draft genome comprised 254 scaffolds with a genome size estimated of 6,096,273 bp. In addition, it has 5250 predicted coding sequences (CDS) and the G + C content is 38.5%. Further, the BCCUSP55 draft genome presented the putative nocuolin A gene complete cluster, a natural oxadiazine that triggers apoptosis in human cancer cells. Thus, our results contribute to extend the knowledge on the genus Sphaerospermopsis and reveal its biotechnological potential. (AU)

• Processo FAPESP: 13/15296-2 - Metagenômica comparativa de florações de cianobactérias em reservatórios de água do estado de Pernambuco
• Beneficiário: Adriana Sturion Lorenzi
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores