| Texto completo | |
| Autor(es): |
Gomes, Mayra Macena
;
Rodrigues da Silva, Maisa Monseff
;
de Araujo, Iana Mizumukai
;
Albuquerque de Paula, Francisco Jose
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ARCHIVES OF ENDOCRINOLOGY METABOLISM; v. 66, n. 5, p. 10-pg., 2022-09-01. |
| Resumo | |
Energy metabolism is a point of integration among the various organs and tissues of the human body, not only in terms of consumption of energy substrates but also because it concentrates a wide interconnected network controlled by endocrine factors. Thus, not only do tissues consume substrates, but they also participate in modulating energy metabolism. Soft mesenchymal tissues, in particular, play a key role in this process. The recognition that high energy consumption is involved in bone remodeling has been accompanied by evidence showing that osteoblasts and osteocytes produce factors that influence, for example, insulin sensitivity and appetite. Additionally, there are significant interactions between muscle, adipose, and bone tissues to control mutual tissue trophism. Not by chance, trophic and functional changes in these tissues go hand in hand from the beginning of an individual's development until aging. Likewise, metabolic and nutritional diseases deeply affect the musculoskeletal system and adipose tissue. The present narrative review highlights the importance of the interaction of the mesenchymal tissues for bone development and maintenance and the impact on bone from diseases marked by functional and trophic disorders of adipose and muscle tissues. (AU) | |
| Processo FAPESP: | 18/18071-5 - Homeostase hidroeletrolítica e energética: do metabolismo celular aos sistemas endócrinos em diferentes fases do desenvolvimento |
| Beneficiário: | Lucila Leico Kagohara Elias |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 21/03152-2 - Interação entre tecido adiposo, muscular e ósseo na anorexia nervosa |
| Beneficiário: | Iana Mizumukai de Araujo |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |