| Texto completo | |
| Autor(es): |
Saldanha, Luiz Leonardo
;
Allard, Pierre-Marie
;
Dilarri, Guilherme
;
Codesido, Santiago
;
Gonzalez-Ruiz, Victor
;
Queiroz, Emerson Ferreira
;
Ferreira, Henrique
;
Wolfender, Jean-Luc
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Journal of Agricultural and Food Chemistry; v. N/A, p. 13-pg., 2022-11-09. |
| Resumo | |
Citrus canker, caused by the bacterium Xanthomonas citri subsp. citri (X. citri), is a plant disease affecting Citrus crops worldwide. However, little is known about defense compounds in Citrus. Here, we conducted a mass spectrometry-based metabolomic approach to obtain an overview of the chemical responses of Citrus leaves to X. citri infection. To facilitate result interpretation, the multivariate analyses were combined with molecular networking to identify biomarkers. Metabolite variations among untreated and X. citri-inoculated Citrus samples under greenhouse conditions highlighted induced defense biomarkers. Notably, the plant tryptophan metabolism pathway was activated, leading to the accumulation of N-methylated tryptamine derivatives. This finding was subsequently confirmed in symptomatic leaves in the field. Several tryptamine derivatives showed inhibitory effects in vitro against X. citri. This approach has enabled the identification of new chemically related biomarker groups and their dynamics in the response of Citrus leaves to Xanthomonas infection. (AU) | |
| Processo FAPESP: | 14/50880-0 - INCT 2014: de genômica comparativa e funcional e melhoramento assistido de citros |
| Beneficiário: | Marcos Antonio Machado |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 19/00307-5 - Investigação da rede de moléculas sinalizadoras de Citrus sinensis infectada com Xanthomonas citri sub. citri usando RMN e UHPLC-TOF/MS com abordagem metabolômica |
| Beneficiário: | Luiz Leonardo Saldanha |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado |
| Processo FAPESP: | 15/50162-2 - Proteção das plantas com peptídeos antimicrobianos e galatos - Pro-Planta |
| Beneficiário: | Henrique Ferreira |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |