| Texto completo | |
| Autor(es): Mostrar menos - |
Pinheiro, Josilene R.
;
dos Reis, Esther C.
;
Farias, Jessica P.
;
Fogaca, Mayanna M. C.
;
da Silva, Patricia de S.
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Santana, Itana Vivian R.
;
Rocha, Ana Luiza S.
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Vidal, Paloma O.
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Simoes, Rafael da C.
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Luiz, Wilson B.
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Birbrair, Alexander
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de Aguiar, Renato S.
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de Souza, Renan P.
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Azevedo, Vasco A. de C.
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Chaves, Gepoliano
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Belmok, Aline
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Duraes-Carvalho, Ricardo
;
Melo, Fernando L.
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Ribeiro, Bergmann M.
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Amorim, Jaime Henrique
Número total de Autores: 20
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| Tipo de documento: | Artigo Científico |
| Fonte: | Viruses-Basel; v. 14, n. 10, p. 12-pg., 2022-10-01. |
| Resumo | |
Background: The correct understanding of the epidemiological dynamics of COVID-19, caused by the SARS-CoV-2, is essential for formulating public policies of disease containment. Methods: In this study, we constructed a picture of the epidemiological dynamics of COVID-19 in a Brazilian population of almost 17000 patients in 15 months. We specifically studied the fluctuations of COVID-19 cases and deaths due to COVID-19 over time according to host gender, age, viral load, and genetic variants. Results: As the main results, we observed that the numbers of COVID-19 cases and deaths due to COVID-19 fluctuated over time and that men were the most affected by deaths, as well as those of 60 or more years old. We also observed that individuals between 30- and 44-years old were the most affected by COVID-19 cases. In addition, the viral loads in the patients' nasopharynx were higher in the early symptomatic period. We found that early pandemic SARS-CoV-2 lineages were replaced by the variant of concern (VOC) P.1 (Gamma) in the second half of the study period, which led to a significant increase in the number of deaths. Conclusions: The results presented in this study are helpful for future formulations of efficient public policies of COVID-19 containment. (AU) | |
| Processo FAPESP: | 19/01255-9 - Morcegos: vigilância epidemiológica, filodinâmica de alta resolução, busca e design de peptídeos de interesse biotecnológico em vírus emergentes e reemergentes |
| Beneficiário: | Ricardo Durães de Carvalho |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 21/03684-4 - Morcegos: vigilância epidemiológica, filodinâmica de alta resolução, busca e design de peptídeos de interesse biotecnológico em vírus emergentes e reemergentes |
| Beneficiário: | Ricardo Durães de Carvalho |
| Modalidade de apoio: | Bolsas no Brasil - Jovens Pesquisadores |