The influence of chitosan, cellulose and alginate chemical nature on mineral matrix formation

Autor(es)

Montrezor, Luis Henrique ; Dercore Benevenuto, Luiz Guilherme ; Antunes, Bruna Fernandes ; Amaral, Andre Capaldo ; Novo, Lisias Pereira ; Felix Carvalho, Antonio Jose ; Trovatti, Eliane

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS; v. 71, n. 12, p. 11-pg., 2021-05-12.

Resumo

Cell carriers such as chitosan, alginate and cellulose play a crucial role in cell behavior, however the influence of their chemical nature on osteogenesis is little studied. Here, rat bone marrow cells were grown on the surface of those polymers. The cells remained viable and produced a mineral matrix, which was deposited on the surface of all the polymers. The amount of inorganic matrix significantly varied according to the polymer, and the morphology of the inorganic matrix was influenced by the nature of the substrates, generating perfect hexagonal crystals at the surface of chitosan, alginate and cellulose. (AU)

• Processo FAPESP: 18/14840-4 - Membranas de celulose bacteriana modificadas superficialmente com plasma para aplicação na engenharia tecidual
• Beneficiário: Luíz Guilherme Dércore Benevenuto
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 16/02811-4 - Laserterapia e terapia celular em ratas induzidas à síndrome do ovário policístico
• Beneficiário: Luis Henrique Montrezor
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/18782-6 - Plataforma click chemistry aplicada ao desenvolvimento de materiais poliméricos para uso em medicina regenerativa
• Beneficiário: Eliane Trovatti
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores