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Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomised crossover trial

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Autor(es):
Geraldi, Marina Vilar ; Cazarin, Cinthia Bau Betim ; Cristianini, Marcelo ; Junqueira Vasques, Ana Carolina ; Geloneze, Bruno ; Marostica Junior, Mario Roberto
Número total de Autores: 6
Tipo de documento: Artigo Científico
Fonte: BRITISH JOURNAL OF NUTRITION; v. 128, n. 8, p. 10-pg., 2021-11-15.
Resumo

Jabuticaba is a Brazilian berry rich in polyphenols, which may exert beneficial effects on metabolic diseases. This randomised crossover study aimed to determine the effects of jabuticaba juice (250 ml in a portion) on postprandial response. Sixteen healthy subjects (eleven women; five men; 28.4 (sd 3.8) years old; BMI 21.7 (sd 2.3) kg/m(-2)) consumed two test products after fasting overnight in a randomised controlled crossover design. Each test product portion had a similar composition of sugar components: 250 ml water with glucose, fructose, coloured with artificial non-energetic food colourings (placebo), and 250 ml of jabuticaba juice. Beverages were administered immediately before a carbohydrate meal. Blood samples were collected at 0, 15, 30, 45, 60, 90 and 120 min after each test product to analyse the concentrations of glucose, insulin, C-peptide, antioxidant capacity, plasma glucagon-like peptide-1 (GLP-1) and appetite sensations. Compared with the placebo, the intake of jabuticaba juice resulted in a higher GLP-1 response as the AUC and peaking at 60 min. Jabuticaba juice also resulted in higher antioxidant capacity. Postprandial glucose, insulin, C-peptide levels and appetite sensations were not significantly different between tests. In conclusion, 250 ml of jabuticaba juice before a carbohydrate meal was able to improve the antioxidant status and GLP-1 concentrations in healthy subjects. (AU)

Processo FAPESP: 15/50333-1 - Cobra: nova plataforma de descoberta de compostos para identificação rápida e de baixo custo de bioativo com efeitos benéficos originários de plantas brasileiras
Beneficiário:Glaucia Maria Pastore
Modalidade de apoio: Auxílio à Pesquisa - Temático
Processo FAPESP: 19/12244-8 - Efeito da suplementação de casca de jabuticaba (Plinia jaboticaba) no perfil metabólico de indivíduos obesos pré-diabéticos: ensaio clínico randomizado, duplo cego, placebo controlado
Beneficiário:Marina Vilar Geraldi
Modalidade de apoio: Bolsas no Brasil - Doutorado