An overview of sulfonamide-based conjugates: Recent advances for tuberculosis treatment

Autor(es)

Scarim, Caue Benito ; Pavan, Fernando Rogerio

• Tipo de documento: Artigo Científico
• Fonte: Drug Development Research; v. 83, n. 3, p. 11-pg., 2022-01-18.

Resumo

In 2019, tuberculosis (TB) caused approximately 1.4 million deaths around the world. TB is an infectious respiratory disease mainly caused by Mycobacterium tuberculosis. The lack of new drugs to treat drug-resistant strains is a principal factor for the continuous slow rise in TB infections. Sulfonamides are active moieties in various drugs used against several sicknesses, including TB. Our aim is to aid the development of new TB treatments and drugs by describing recent improvements (2011-2021) to sulfonamide-based compounds. (AU)

• Processo FAPESP: 16/10847-9 - Hidroximetilnitrofural (NFOH): estudo da atividade em fase crônica da Doença de Chagas em modelo animal e síntese de derivados solúveis
• Beneficiário: Cauê Benito Scarim
• Modalidade de apoio: Bolsas no Brasil - Doutorado