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Genes and proteins associated with ribeye area and meat tenderness in a commercial Nellore cattle population

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Autor(es):
Frezarim, Gabriela B. ; Fonseca, Larissa F. S. ; Salatta, Bruna M. ; Silva, Danielly B. S. ; Bresolin, Tiago ; Seno, Leonardo de Oliveira ; Barufatti, Alexeia ; Ferro, Jesus Aparecido ; Albuquerque, Lucia Galvao
Número total de Autores: 9
Tipo de documento: Artigo Científico
Fonte: GENOME; v. 65, n. 4, p. 12-pg., 2022-04-01.
Resumo

Despite several studies on genetic markers and differentially expressed genes related to ribeye area (REA) and tenderness traits in beef cattle, there is divergence in the results regarding the genes associated with these traits. Thirteen genes associated with or exhibiting biological functions that might influence such phenotypes were included in this study. A total of five genes for REA (IGF-1, IGF-2, MSTN, NEDD4, and UBE4A) and eight genes for meat tenderness (CAPN1, CAPN2, CAST, HSPB1, DNAJA1, FABP4, SCD, and PRKAG3) were selected from previous studies on beef cattle. Genes and their respective proteins expression were validated in a commercial population of Nellore cattle using quantitative real- time PCR (RT-qPCR) and advanced mass spectrometry (LC/MS-MS) techniques, respectively. The MSTN gene was upregulated in animals with low REA. The CAPN1, CAPN2, CAST, HSPB1, and DNAJA1 genes were upregulated in animals with tough meat. The proteins translated by these genes were not differentially expressed. Our results confirm the potential of some of the studied genes as biomarkers for carcass and meat quality traits in Nellore cattle. (AU)

Processo FAPESP: 18/20026-8 - EMU concedido no processo 2017/10630-2: servidor
Beneficiário:Lucia Galvão de Albuquerque
Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
Processo FAPESP: 17/10630-2 - Aspectos genéticos da qualidade, eficiência e sustentabilidade da produção de carne em animais da raça Nelore
Beneficiário:Lucia Galvão de Albuquerque
Modalidade de apoio: Auxílio à Pesquisa - Temático
Processo FAPESP: 16/23937-6 - Expressão de genes e proteínas relacionados à qualidade da carne em bovinos Nelore
Beneficiário:Lucia Galvão de Albuquerque
Modalidade de apoio: Auxílio à Pesquisa - Regular