| Texto completo | |
| Autor(es): |
Gusmao, Luiza Araujo
;
Matsuo, Flavia Sayuri
;
Barbosa, Hellen Franciane Goncalves
;
Tedesco, Antonio Claudio
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | FRONTIERS IN NANOTECHNOLOGY; v. 4, p. 14-pg., 2022-08-31. |
| Resumo | |
The development of nano-based materials for diagnosis enables a more precise prognosis and results. Inorganic, organic, or hybrid nanoparticles using nanomaterials, such as quantum dots, extracellular vesicle systems, and others, with different molecular compositions, have been extensively explored as a better strategy to overcome the blood-brain barrier and target brain tissue and tumors. Glioblastoma multiforme (GBM) is the most common and aggressive primary tumor of the central nervous system, with a short, established prognosis. The delay in early detection is considered a key challenge in designing a precise and efficient treatment with the most encouraging prognosis. Therefore, the present mini-review focuses on discussing distinct strategies presented recently in the literature regarding nanostructures' use, design, and application for GBM diagnosis. (AU) | |
| Processo FAPESP: | 13/50181-1 - Utilização de nanocarreadores contendo fármacos fotossensibilizantes e outros ativos aplicados à terapia celular e tratamento de patologias do sistema nervoso central |
| Beneficiário: | Antonio Claudio Tedesco |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 18/17911-0 - Nanocarreador lipídico revestido com polímero aplicado na veiculação de agentes terapêuticos para o diagnóstico e o tratamento de patologias do sistema nervoso central via administração intranasal |
| Beneficiário: | Hellen Franciane Gonçalves Barbosa |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |