| Texto completo | |
| Autor(es): |
Santos, Hugo
;
Zeoly, Lucas A.
;
Rodrigues Jr, Manoel T.
;
Fernandes, Fabio S.
;
Gomes, Ralph C.
;
Almeida, Wanda P.
;
Coelho, Fernando
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ACS CATALYSIS; v. 13, n. 6, p. 32-pg., 2023-03-17. |
| Resumo | |
Since its discovery in the late 1960s, the Morita-Baylis-Hillman (MBH) reaction has remained a powerful carbon- carbon sigma-bond-forming transformation, producing small polyfunctionalized molecules. While commonly catalyzed by Lewis basic organic molecules such as tertiary amines and phosphines, several advances in functional catalysts and reaction conditions have been made in order to improve the reaction rate, substrate scope, and enantioselectivity. The goal of this Review is to give an updated summary of the main improvements made in catalytic systems for the MBH reaction over the past decade until nowadays. We hope this account will instigate further investigations in order to circumvent the remaining challenges of this fascinating transformation. (AU) | |
| Processo FAPESP: | 13/07600-3 - CIBFar - Centro de Inovação em Biodiversidade e Fármacos |
| Beneficiário: | Glaucius Oliva |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |
| Processo FAPESP: | 15/09205-0 - Novas fronteiras da reação de Morita-Baylis-Hillman: 1) Novas aplicações de um catalisador bifuncional derivado do imidazol. 2) Estudos visando à síntese assimétrica de um adoçante natural com alto potencial dulcífero |
| Beneficiário: | Hugo dos Santos |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado Direto |