Estimating HIV-1 Incidence Using the Serologic Testing Algorithm for Recent HIV Seroconversion at HIV Counseling and Testing Centers in the City of Sao Paulo, Brazil

Autor(es)

Bassichetto, Katia ; Bergamaschi, Denise ; Veras, Maria ; Araripe Sucupira, Maria ; Mesquita, Fabio ; Diaz, Ricardo

• Tipo de documento: Artigo Científico
• Fonte: American Journal of Infectious Diseases; v. 4, n. 4, p. 5-pg., 2008-01-01.

Resumo

The network of HIV counseling and testing centers in Sao Paulo, Brazil is a major source of data used to build epidemiological profiles of the client population. In this study, HIV-1 incidence from November of 2000 to April of 2001 was estimated, comparing recently infected individuals to those with long-standing infection in terms of epidemiological and socio-behavioral aspects. To identify recent infection, less sensitive ELISA was employed. The overall incidence of HIV-1 infection among the clients was 0.53/100/year (95% CI: 0.31-0.85/100/year): 0.77/100/year for males (95% CI: 0.42-1.27/100/year) and 0.22/100/year (95% CI: 0.05-0.59/100/year) for females. Overall HIV-1 prevalence was 3.2% (95% CI: 2.8-3.7%), being 4.0% among males (95% CI: 3.3-4.7%) and 2.1% among females (95% CI: 1.6-2.8%). Recent infections accounted for 15% of the total (95% CI: 10.2-20.8%). Recent infection correlated with being younger and male (p = 0.019). Therefore, recent infection was more common among younger males and older females. (AU)

• Processo FAPESP: 98/14381-4 - Determinação da prevalência de resistência genotípica e da diversidade genética em casos de infecção recente pelo Vírus da Imunodeficiência Humana (HIV-1)
• Beneficiário: Ricardo Sobhie Diaz
• Modalidade de apoio: Auxílio à Pesquisa - Temático