Chiral Chalcogen Peptides as Ligands for the Catalytic Enantioselective Aryl Transfer Reaction to Aldehydes

Autor(es)

Schwab, Ricardo S. ; Soares, Letiere C. ; Dornelles, Luciano ; Rodrigues, Oscar E. D. ; Paixao, Marcio W. ; Godoi, Marcelo ; Braga, Antonio L.

• Tipo de documento: Artigo Científico
• Fonte: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; v. 2010, n. 19, p. 5-pg., 2010-07-01.

Resumo

A new series of chiral chalcogen peptides were synthesized from inexpensive and commercially available starting materials. The synthesized compounds were tested as catalysts in the enantioselective arylation of aldehydes by using arylboronic acids as the aryl source. The desired diarylmethanols were obtained in excellent yields and with enantioselectivities up to 91% ee. (AU)

• Processo FAPESP: 09/14352-0 - Organocatálise assimétrica: preparação de novos organocatalisadores e desenvolvimento de novas metodologias
• Beneficiário: Márcio Weber Paixão
• Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores
• Processo FAPESP: 09/07281-0 - Organocatálise assimétrica: preparação de novos organocatalisadores e desenvolvimento de novas metodologias
• Beneficiário: Márcio Weber Paixão
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores