Pharmacist-physician collaborative care model for patients with uncontrolled type 2 diabetes in Brazil: results from a randomized controlled trial

Autor(es)

Aguiar, Patricia M. ; da Silva, Claudio Henrique P. ; Chiann, Chang ; Dorea, Egidio Lima ; Lyra, Divaldo P., Jr. ; Storpirtis, Silvia

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF EVALUATION IN CLINICAL PRACTICE; v. 24, n. 1, p. 9-pg., 2018-02-01.

Resumo

Rationale, aims and objectivesThis study aimed to evaluate the effect of a pharmacist-physician collaborative care model on clinical outcomes in patients with uncontrolled type 2 diabetes and determine characteristics that influence this effect. MethodsA randomized controlled trial was conducted in a secondary care clinic for 80 patients with type 2 diabetes, aged 40-79years and glycosylated haemoglobin (A1C) level7.0%. The intervention group received individual, face-to-face pharmaceutical consultations and remote telephone support after a routine visit. The main measures were clinical outcomes (A1C, blood pressure, LDL cholesterol) and process indicators (medication adherence, medication regimen complexity, use of medicines). Multiple regression models were used to determine the variables that could explain the reduction and individualized control of A1C. ResultsFrom the initial sample of 80 patients, 73 completed this study. Compared with usual care, patients in the intervention group showed greater reduction in A1C (-0.79 vs. -0.16; P=0.010); and an increase in the percentage of patients achieving the individualized goal of A1C (25.0% vs. 5.4%; P=0.020). In addition, there was an increase in the percentage of adherent patients and in the average scores of medication adherence. Participation in the intervention group, higher baseline A1C levels and greater change in medication adherence were all significant predictors of improvement in A1C levels. ConclusionsThe results suggest that the collaborative care model proposed is feasible and more effective than the usual care in the reduction and individualized control of A1C levels in patients with uncontrolled type 2 diabetes. (AU)

• Processo FAPESP: 11/11145-4 - Impacto da atenção farmacêutica sobre o manejo da hipertensão não controlada em pacientes idosos com Diabetes Mellitus tipo II
• Beneficiário: Silvia Storpirtis
• Modalidade de apoio: Auxílio à Pesquisa - Regular