Electrochemical sensor for estriol hormone detection in biological and environmental samples

Autor(es)

Jodar, Leticia Vieira ; Santos, Fabricio Aparecido ; Zucolotto, Valtencir ; Janegitz, Bruno Campos

• Tipo de documento: Artigo Científico
• Fonte: Journal of Solid State Electrochemistry; v. 22, n. 5, p. 8-pg., 2018-05-01.

Resumo

A stable conducting film for sensing using reduced graphene oxide (RGO), gold nanoparticles (GNPs), and potato starch (PS) is proposed. The characterization of the nanomaterials was obtained by ultraviolet and visible spectroscopy, dynamic light scattering, zeta potential, Fourier transform infrared spectroscopy, atomic force microscopy, and cyclic voltammetry. The voltammetric behavior of the RGO-GNPs-PS/GCE electrodes was studied in the presence of estriol and the results showed a high anodic peak current at 0.64 V. Under optimal conditions, an analytical curve was obtained, in which the anodic peak estriol was linear in the range from 1.5 to 22 mu mol L-1, with a detection limit of 0.48 mu mol L-1. The modified electrodes were applied for determination of estriol in environmental and biological samples. The proposed electrode was used for estriol determination in water and urine samples, which presented a recovery range from 92.1 to 106%, showing that RGO-GNPs-PS/GCE is a viable alternative for the detection of estriol and can be attractive for several electrochemical applications. (AU)

• Processo FAPESP: 15/19099-2 - Desenvolvimento de sensores e biossensores eletroquímicos para diversos fins analíticos
• Beneficiário: Bruno Campos Janegitz
• Modalidade de apoio: Auxílio à Pesquisa - Regular