| Texto completo | |
| Autor(es): |
Souza, Fernando N.
[1]
;
Monteiro, Andrea M.
[2]
;
dos Santos, Priscilla R.
[3]
;
Ramos Sanchez, Eduardo M.
[2]
;
Blagitz, Maiara G.
[1]
;
Latorre, Andreia O.
[4]
;
Figueiredo Neto, Antonio M.
[3]
;
Gidlund, Magnus
[2]
;
Della Libera, Alice M. M. P.
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Fac Vet Med & Anim Sci, Dept Clin Sci, BR-05508270 Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Immunol, BR-05508900 Sao Paulo - Brazil
[3] Univ Sao Paulo, Inst Phys, BR-05315970 Sao Paulo - Brazil
[4] Univ Sao Paulo, Fac Vet Med & Anim Sci, Dept Pathol, BR-05508270 Sao Paulo - Brazil
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; v. 143, n. 1-2, p. 162-166, SEP 15 2011. |
| Citações Web of Science: | 9 |
| Resumo | |
Bovine leukemia virus (BLV) is among the most widespread livestock pathogens in many countries. Despite advances in understanding the pathogenesis of this disease, little is known about the involvement of oxidative stress. Therefore, this study examined the antioxidant status and the markers of oxidative stress in BLV-infected dairy cows. BLV infection was associated with an increase in triacylglycerol levels, a decrease in glutathione peroxidase (GSH-Px) activity and a tendency toward lower superoxide dismutase activity in the infected animals. No significant difference was observed in other markers of oxidative stress (i.e., conjugated dienes, hydroperoxides and malondialdehyde) in the infected animals compared to controls. A novel method for the analysis of oxidative stress, Z-scan based on the measurement of the mean-value of 9 in low density lipoprotein indicated that the infected animals had low-density lipoprotein particles that were slightly less modified than those from the healthy group. Thus, we conclude that BLV infection is associated with a selective decrease in GSH-Px activity without any alteration in the common plasma markers of oxidative stress. (C) 2011 Elsevier B.V. All rights reserved. (AU) | |
| Processo FAPESP: | 07/56069-8 - Avaliacao do efeito do estresse oxidativo na resposta imune de bovinos infectados pelo virus da leucose enzootica bovina. |
| Beneficiário: | Alice Maria Melville Paiva Della Libera |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |