Toxic Effects of Biogenic and Synthesized Silver Nanoparticles on Sea Urchin Echinometra lucunter Embryos

Autor(es)

Bruni, Mariana ; Ottoni, Cristiane ; Abessa, Denis

• Tipo de documento: Artigo Científico
• Fonte: Bulletin of Environmental Contamination and Toxicology; v. 113, n. 3, p. 6-pg., 2024-09-01.

Resumo

Due to their broad-spectrum antimicrobial action and ease of synthesis, silver nanoparticles (AgNP) are one of the most widely used nanomaterials in different industrial and ecological areas. AgNP are released into marine ecosystems, nevertheless, their ecotoxicological effects have been overlooked. In this study, we evaluated the toxic effects of biogenic and synthesized AgNP (AgNPIBCLP11 and AgNPSINT) on sea urchin Echinometra lucunter embryos and compared them with the metal precursor silver nitrate (AgNO3). Fertilized eggs were exposed to five concentrations of the test compounds and a negative control for 48 h under controlled conditions. The IC50-48 h of AgNPIBCLP11, AgNPSINT and AgNO3 were 0.31, 4.095, and 0.01 mu g L-1, evidencing that both AgNP are less toxic than AgNO3, and that AgNPSINT is less toxic than the AgNPIBCLP11. Toxicity to E. lucunter embryos could be explained by the fact that Ag affects DNA replication and induces the formation of pores in the cellular wall, leading to apoptosis. (AU)

• Processo FAPESP: 20/12867-2 - Desenvolvimento e validação de uma tecnologia inovadora de baixo custo, baseada em uma bio- e nano- abordagem na desinfecção da água potável
• Beneficiário: Cristiane Angélica Ottoni
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Regular
• Processo FAPESP: 20/03004-0 - Avaliação da bioacumulação e toxicidade de nanomateriais anti-incrustantes inovadores em invertebrados marinhos neotropicais e subtropicais
• Beneficiário: Denis Moledo de Souza Abessa
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Regular
• Processo FAPESP: 18/25379-6 - Estudo da toxicidade de nanopartículas de prata (AgNP) sobre estágios embrionários de ouriço do mar Echinometra lucunter
• Beneficiário: Mariana Bruni Marques do Prado e Silva
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica