Fourteen weeks of β-alanine supplementation and HIIT did not improve serum BDNF concentrations and Stroop test performance

Autor(es)

Mendonca, Paloma Tavares ; Dutra, Yago Medeiros ; Antunes, Barbara M. ; Lira, Fabio ; Zagatto, Alessandro Moura

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. N/A, p. 10-pg., 2025-01-20.

Resumo

This study aimed to investigate whether 14 weeks of beta-alanine supplementation and high-intensity intermittent training improves brain-derived neurotrophic factor concentrations and cognitive aspects related to executive functions assessed by the Stroop test. Thirteen healthy and active men underwent a 4-week supplementation period (beta-alanine: 6.4 g/d or a placebo) followed by 10-week supplementation combined with high-intensity intermittent training, totaling 14 weeks of intervention. Participants underwent a graded exercise test, while the blood samples for brain-derived neurotrophic factor analysis and the Stroop test (cognitive task) were assessed before and after a high-intensity intermittent exercise (10 runs of 1:1 min effort and a pause ratio at 130% of respiratory compensation point). These measurements were performed three times across the study being at baseline, after 4 weeks of supplementation (POST4weeks) and at the end of the 14 weeks of study (POST14weeks). Compared to baseline values, there were no improvements in brain-derived neurotrophic factor concentrations or Stroop test performance with either beta-alanine or high-intensity intermittent training. Lactate peak concentrations in a high-intensity intermittent exercise session also did not differ between groups. However, high-intensity intermittent training did improve some cardiorespiratory parameters (i.e., intensity associated with VO2max p=0.01 and respiratory compensation point, p=0.01). In conclusion, beta-alanine supplementation alone or associated with high-intensity intermittent training did not improve the brain-derived neurotrophic factor concentrations and Stroop test performance in healthy men. (AU)

• Processo FAPESP: 21/08479-0 - Time course da recuperação neuromuscular após sessão de treino de corrida: influência da intensidade, da imersão em água quente e da imersão em água fria
• Beneficiário: Yago Medeiros Dutra
• Modalidade de apoio: Bolsas no Brasil - Doutorado