Toxicity Assessment of Biogenic Gold Nanoparticles on Crop Seeds and Zebrafish Embryos: Implications for Agricultural and Aquatic Ecosystems

Autor(es)

Botteon, Caroline E. A. ; Pereira, Anderson do E. S. ; de Castro, Larissa P. ; Justino, Isabela A. ; Fraceto, Leonardo F. ; Bastos, Jairo K. ; Marcato, Priscyla D.

• Tipo de documento: Artigo Científico
• Fonte: ACS OMEGA; v. 10, n. 1, p. 15-pg., 2025-01-03.

Resumo

The demand for food production has been growing exponentially due to the increase in the global population. Innovative approaches to enhance agricultural productivity have been explored, including the new applications of nanoparticles in agriculture. The nanoparticle application in agriculture can generate environmental and human health risks since nanoparticles can contaminate the soil and inevitably reach groundwater, potentially causing toxicity in aquatic organisms. In this study, we evaluated the benefits and toxicity of gold nanoparticles (GNPs), synthesized via green chemistry, on the growth of cultivated plants and in the zebrafish embryo model. GNPs were synthesized through an economical and environmentally friendly method using Brazilian red propolis (BRP) extract (BRP-GNPs). BRP-GNPs exhibited negative and positive effects on plant germination, depending on the concentration tested and the plant species involved. Moreover, BRP-GNPs induced developmental toxicity in fish embryos in a dose-dependent manner. Our results provide valuable insights for assessing the environmental risks of biogenic GNPs. (AU)

• Processo FAPESP: 17/04138-8 - Realização de estudos químicos, analíticos, biológicos, farmacológicos e tecnológicos para preenchimento das lacunas no desenvolvimento do setor de própolis brasileiro
• Beneficiário: Jairo Kenupp Bastos
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 18/13465-5 - Desenvolvimento de nanopartículas poliméricas contendo própolis vermelha brasileira e avaliação antitumoral in vitro e in vivo em cânceres urológicos
• Beneficiário: Priscyla Daniely Marcato Gaspari
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 21/10639-5 - Centro de Pesquisa em Biodiversidade e Mudanças do Clima
• Beneficiário: Leonor Patricia Cerdeira Morellato
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 14/50928-2 - INCT 2014: Nanotecnologia Farmacêutica: uma abordagem transdisciplinar
• Beneficiário: Maria Vitória Lopes Badra Bentley
• Modalidade de apoio: Auxílio à Pesquisa - Temático