| Texto completo | |
| Autor(es): |
Martinez, Alice K. de A.
;
Mourao, Penina S.
;
Correa, Arlene G.
Número total de Autores: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Synlett; v. N/A, p. 9-pg., 2025-03-12. |
| Resumo | |
Epoxides and aziridines are important pharmacologically active compounds that are found in many drugs. These three-membered rings are also employed in the synthesis of a wide range of other heterocycles. In this account, we highlight the contributions of our research group to the organocatalyzed asymmetric synthesis of epoxides and aziridines from a,(3-unsaturated carbonyl compounds, followed by multicomponent reactions that afford novel peptidomimetics. Additionally, these scaffolds have been employed in the synthesis of lac- tones, lactams, and hydantoins, showcasing their versatility in drug development and synthetic chemistry. (AU) | |
| Processo FAPESP: | 24/05518-2 - Síntese de N-heterociclos de cinco membros empregando métodos verdes |
| Beneficiário: | Alice Karoline de Almeida Martinez |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado Direto |
| Processo FAPESP: | 21/12394-0 - Métodos sintéticos sustentáveis empregando catálise, solventes verdes, reagentes seguros e materiais de partida renováveis |
| Beneficiário: | Arlene Gonçalves Corrêa |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |