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Quaternized cassava starch-based film reinforced by nanocrystalline cellulose with antimicrobial activity against bacteria and coronavirus

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Autor(es):
de Carvalho, Guilherme Ribeiro ; Netto, Rafael Affonso ; Delarmelina, Camila ; Duarte, Marta Cristina Teixeira ; Lona, Liliane Maria Ferrareso
Número total de Autores: 5
Tipo de documento: Artigo Científico
Fonte: EXPRESS POLYMER LETTERS; v. 19, n. 7, p. 11-pg., 2025-07-01.
Resumo

In this study, a new plastic film with antiviral and antibacterial properties was developed using modified cassava starch with glycidyltrimethylammonium chloride (GTMAC) and reinforced by crystalline nanocellulose (CNC), called Q-CS/CNC. For comparison, a control film (Q-CS) was produced without the addition of CNC. Elemental analysis revealed a degree of substitution (DS) of 0.552, indicating the replacement of the OH groups of starch by the NR4+ groups of GTMAC during the quaternization reaction. The addition of CNC resulted in significant increases (p < 0.05) of 38.9, 38.2, and 43.1% in thickness, opacity, and water vapor permeability measurements, respectively, compared to Q-CS. Incorporating CNC also contributed to an increase of 43.6% in tensile strength and 109% in stiffness but slightly decreased thermal stability. The Q-CS/CNC film demonstrated efficacy by inactivating 99% of the coronavirus in 1 min and inhibiting the growth of Staphylococcus aureus and Escherichia coli. This action is attributed to the electrostatic interaction of quaternary amino groups, grafted onto starch, with the phospholipid membrane of microorganisms, resulting in the inactivation of these microorganisms. Therefore, these results highlight the potential use of Q-CS/CNC film as antimicrobial packaging, especially against coronavirus. (AU)

Processo FAPESP: 23/12419-8 - Valorização da celulose e lignina para a produção de materiais com potencial aplicação nas áreas médica e de embalagem
Beneficiário:Liliane Maria Ferrareso Lona
Modalidade de apoio: Auxílio à Pesquisa - Regular