| Texto completo | |
| Autor(es): |
Ferreira, Gabriella Nunes
;
da Costa, Rafael Ravagnani
;
Paixao, Guilherme A.
;
Jaison Junior, M.
;
Correa, Thaila Q.
;
de Aguiar, Antonio S. N.
;
Lima, Alessandra R.
;
Bagnato, Vanderlei S.
;
Yoshioka, Sergio A.
;
Dias, Lucas D.
Número total de Autores: 10
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY; v. 272, p. 11-pg., 2025-09-23. |
| Resumo | |
The development of protein-based films derived from plants and agricultural sources has gained significant attention in the medical and food industries due to their broad applicability, sustainability, low cost, and nontoxic nature. Over the years, numerous studies have reported (photo)antimicrobial films aligned with the principles of the circular economy. In this study, zein-based films immobilized with curcumin as a photosensitizer (2.5 % and 5 % w/w) were synthesized and fully characterized using UV-Vis spectroscopy, fluorescence analysis, FT-IR, thermogravimetry (TG), and water contact angle measurements. Their potential for photodynamic applications was assessed through photobleaching analysis, confirming the generation of reactive oxygen species (ROS) at both concentrations. Furthermore, microbiological evaluations were conducted against Staphylococcus aureus biofilms under two different lighting regimes: continuous and intermittent exposure at specific time intervals (0, 6, 12, 18, and 24 h). The films demonstrated promising antimicrobial activity, achieving bacterial inactivation of up to 3.5 log reductions. These findings highlight the potential applications of zeincurcumin films as coatings for medical devices (e.g., endotracheal tubes, catheters) and as sustainable food packaging materials. The incorporation of photoantimicrobial properties into biodegradable films opens new perspectives for their use in healthcare and food preservation. (AU) | |
| Processo FAPESP: | 14/50857-8 - INCT 2014 - de Óptica Básica e Aplicada às Ciências da Vida |
| Beneficiário: | Vanderlei Salvador Bagnato |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 13/07276-1 - CEPOF - Centro de Pesquisa em Óptica e Fotônica |
| Beneficiário: | Vanderlei Salvador Bagnato |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |
| Processo FAPESP: | 19/27176-8 - Fotocatálise assimétrica aplicada à síntese do medicamento Brivaracetam: abordagens sintéticas empregando tecnologias facilitadoras de síntese química |
| Beneficiário: | Kleber Thiago de Oliveira |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 23/11853-6 - Estudo da suplementação fotônica e mecanismos de incorporação de ativos farmacêuticos em cultivo hidropônico |
| Beneficiário: | Alessandra Ramos Lima |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 20/06874-6 - Aplicações das metodologias e tecnologias de síntese em regime de fluxo contínuo desenvolvidas no LQBO-UFSCar na preparação de moléculas com atividades biológicas e IFAs |
| Beneficiário: | Kleber Thiago de Oliveira |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |