| Texto completo | |
| Autor(es): |
Borghi-Silva, Audrey
[1]
;
Arena, Ross
[2, 3, 4]
;
Castello, Viviane
[1]
;
Simoes, Rodrigo Polaquini
[1]
;
Barreto Martins, Luis Eduardo
[5]
;
Cataii, Aparecida Maria
[1]
;
Costa, Dirceu
[6]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Fed Sao Carlos, Cardiopulm Physiotherapy Lab, Nucleus Res Phys Exercise, Dept Physiotherapy, UFSCar, BR-13565905 Sao Carlos, SP - Brazil
[2] Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA - USA
[3] Virginia Commonwealth Univ, Dept Physiol, Richmond, VA - USA
[4] Virginia Commonwealth Univ, Dept Phys Therapy, Richmond, VA - USA
[5] Univ Estadual Campinas, Fac Phys Educ, Exercise Physiol Lab, Campinas, SP - Brazil
[6] Univ 9 Julho, Phys Therapy Dept, Sao Paulo - Brazil
Número total de Afiliações: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | RESPIRATORY MEDICINE; v. 103, n. 10, p. 1503-1510, OCT 2009. |
| Citações Web of Science: | 52 |
| Resumo | |
Objectives: Autonomic modulation is adversely impacted in patients with chronic obstructive pulmonary disease (COPD). The purpose of the present investigation is to assess the effects of a 6-week aerobic exercise training program on autonomic modulation of heart rate in patients with COPD. Methods: Forty patients of both sexes with moderate-to-severe COPD were randomly allocated to aerobic exercise training (PT, n = 20) or to usual care (Control, n = 20). The training program consisted of tower and upper limb stretching and 30 min of treadmill. exercise, 3 times per week for a 6-week period. Physiological data during symptom-limited exercise testing and the six-minute walk test (6MWT) were assessed. In addition, R-R intervals were obtained at rest and during the 6MWT. Heart rate variability was analyzed by time (rMSSD and SDNN index) and frequency domains (high frequency - HF, low frequency - LF and HF/LF ratio). Results: Peak oxygen consumption significantly improved in the training group only (p < 0.05). Moreover, the training group demonstrated significant improvements (p < 0.05) in blood lactate, minute ventilation, dyspnea at peak exercise, sympathetic activity, and parasympathetic activity at rest and during submaximal exercise. Lastly, a positive and significant correlation was found between change in 6MWT distance and rMSSD index (r = 0.65 and p = 0.001). Conclusions: Neural control of heart rate, in addition to other clinically valuable measures, is positively altered in moderate-severe COPD patients following 6 weeks of aerobic exercise training. The improvement in submaximal performance after exercise training was associated with parasympathetic activity. Published by Elsevier Ltd. (AU) | |
| Processo FAPESP: | 05/59427-7 - Efeito da modulação autonômica cardíaca em pacientes submetidos à cirurgia de revascularização do miocárdio e programa de fisioterapia: fase I da reabilitação cardiovascular |
| Beneficiário: | Audrey Borghi Silva |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |