In vitro and clinical evaluation of specific dentifrices for complete denture hygiene

Autor(es)

Panzeri, Heitor ^[1] ; Guimaraes Lara, Elza Helena ^[2] ; Oliveira Paranhos, Helena de Freitas ^[1] ; Lovato da Silva, Claudia Helena ^[1] ; de Souza, Raphael Freitas ^[1] ; Monteiro de Souza Gugelmin, Maria Cristina ^[3] ; Tirapelli, Camila ^[1] ; Cruz, Patricia Costa ^[1] ; de Andrade, Ingrid Machado ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Ribeirao Preto Dent Sch, Dept Dent Mat & Prosthodont, BR-14040904 Ribeirao Preto, SP - Brazil

^[2] Univ Sao Paulo, Ribeirao Preto Fac Pharmaceut Sci, Dept Pharmaceut Sci, BR-14040904 Ribeirao Preto, SP - Brazil

^[3] Univ Sao Paulo, Ribeirao Preto Fac Pharmaceut Sci, Dept Clin Toxicol & Bromatol Anal, BR-14040904 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: GERODONTOLOGY; v. 26, n. 1, p. 26-33, MAR 2009.
• Citações Web of Science: 19

Resumo

To study the physical properties of two experimental dentifrices for complete denture hygiene, their effect on denture biofilm removal and antimicrobial properties by means of a clinical trial. The experimental dentifrices comprised two compositions. One was based on the addition of 1% chloramine T (D1) and the other on the presence of 0.01% fluorosurfactant (D2). Measurements of density, pH, consistency, rheological features and abrasiveness were conducted. Sixty complete denture wearers were randomly assigned to three groups and were instructed to brush their dentures with a specific toothbrush: (1) Water (control); (2) D1; or (3) D2. Each method was used for 21 days. Denture biofilm was disclosed by a 1% neutral red solution and quantified by means of digital photos taken from the internal surface. Microbiological assessment was conducted to quantify Candida sp. and mutans streptococci. Data were evaluated by one-way anova and Tukey HSD, or Kruskal-Wallis (alpha = 0.05). Both dentifrices decreased biofilm coverage when compared with the control group. D1 was the most efficacious treatment to reduce mutans streptococci, whereas D2 showed an intermediate outcome (anova, p < 0.040). No treatment influenced Candida albicans or non-albicans species (Kruskal-Wallis, p = 0.163 and 0.746, respectively). It can be concluded that brushing complete dentures with the experimental dentifrices tested could be effective for the removal of denture biofilm. (AU)

• Processo FAPESP: 05/55705-2 - Avaliação da ação antimicrobiana de soluções de gluconato de clorexidina, pastilhas efervescentes de ultra-som sobre leveduras do gênero Candida e sobre Streptococcus mutans e Streptococcus sobrinus presentes em próteses totais
• Beneficiário: Maria Cristina Monteiro de Souza Gugelmin
• Modalidade de apoio: Auxílio à Pesquisa - Regular