Daily variations in human plasma fluoride concentrations

Autor(es)

Cardoso, Vanessa E. S. ^[1] ; Whitford, Gary M. ^[2] ; Aoyama, Hiroshi ^[3] ; Buzalaf, Marilia A. R. ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Chem, BR-05508900 Sao Paulo - Brazil

^[2] Med Coll Georgia, Dept Oral Biol, Sch Dent, Augusta, GA 30912 - USA

^[3] Univ Estadual Campinas, Dept Biochem, BR-13083862 Campinas, SP - Brazil

^[4] Univ Sao Paulo, Bauru Dent Sch, Dept Biol Sci Biochem, BR-17012901 Bauru, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF FLUORINE CHEMISTRY; v. 129, n. 12, p. 1193-1198, DEC 2008.
• Citações Web of Science: 5

Resumo

This study investigated the variations in human plasma fluoride concentrations ({[}F]) and sought to determine the causes. Five subjects (27-33 years old) received a low-F diet during the 5 days of the study. Plasma samples and urine were collected every 3 h from 8 a.m. to 8 p.m. F, PTH, Ca and P were analyzed with the electrode, by chemiluminescence, AAS and colorimetry, respectively. A trend for the plasma {[}F] was found. The peak {[}F], 0.55 +/- 0.11 mu mol L(-1), occurred at 11 a.m. and the lowest {[}F], 0.50 +/- 0.06 mu mol L(-1) occurred between 5 and 8 p.m. Plasma {[}F] were positively correlated with urinary F excretion rates and with serum PTH levels, but not with the Ca or P levels. Serum PTH levels were positively correlated with urinary F excretion rates and negatively correlated with plasma Ca. The results suggest that the renal system seems to control the daily fluctuations in plasma {[}F]. (c) 2008 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 02/10489-2 - Influência do ritmo circadiano no metabolismo do flúor em humanos
• Beneficiário: Marília Afonso Rabelo Buzalaf
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 02/10361-6 - Influência do ritmo circadiano no metabolismo do flúor em humanos
• Beneficiário: Vanessa Eid da Silva Cardoso
• Modalidade de apoio: Bolsas no Brasil - Mestrado