Detection of a New Yellow Fever Virus Lineage Within the South American Genotype I in Brazil

Autor(es):Mostrar menos -

de Souza, Renato P. ^[1] ; Foster, Peter G. ^[2] ; Sallum, Maria Anice M. ^[3] ; Coimbra, Terezinha L. M. ^[1] ; Maeda, Adriana Y. ^[1] ; Silveira, Vivian R. ^[1] ; Moreno, Eduardo S. ^[1] ; da Silva, Fernanda G. ^[1] ; Rocco, Iray M. ^[1] ; Ferreira, Ivani B. ^[1] ; Suzuki, Akemi ^[1] ; Oshirog, Fabiola M. ^[1] ; Petrella, Selma M. C. N. ^[1] ; Pereira, Luiz E. ^[1] ; Katz, Giselda ^[4] ; Tengan, Cilea H. ^[4] ; Siciliano, Melissa M. ^[4] ; dos Santos, Cecilia L. S. ^[1]

Afiliação do(s) autor(es)

^[1] Inst Adolfo Lutz Registro, Serv Virol, BR-01246902 Sao Paulo - Brazil

^[2] Nat Hist Museum, Dept Zool, London SW7 5BD - England

^[3] Univ Sao Paulo, Fac Saude Publ, Dept Epidemiol, BR-01255 Sao Paulo - Brazil

^[4] Ctr Vigilancia Epidemiol, Div Zoonoses, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Medical Virology; v. 82, n. 1, p. 175-185, JAN 2010.
• Citações Web of Science: 33

Resumo

Nucleotide sequences of two regions of the genomes of 11 yellow fever virus (YFV) samples isolated from monkeys or humans with symptomatic yellow fever (YF) in Brazil in 2000,2004, and 2008 were determined with the objective of establishing the genotypes and studying the genetic variation. Results of the Bayesian phylogenetic analysis showed that sequences generated from strains from 2004 and 2008 formed a new subclade within the clade 1 of the South American genotype I. The new subgroup is here designated as 1E. Sequences of YFV strains recovered in 2000 belong to the subclade 1D, which comprises previously characterized YFV strains from Brazil. Molecular dating analyses suggested that the new subclade 1E started diversifying from 1D about 1975 and that the most recent 2004-2008 isolates arose about 1985. J. Med. Virol. 82:175-185, 2010. (C) 2009 Wiley-Liss, Inc. (AU)

• Processo FAPESP: 05/53973-0 - Sistemática de Anopheles (Nyssorhynchus) (Diptera: Culicidae)
• Beneficiário: Maria Anice Mureb Sallum
• Modalidade de apoio: Auxílio à Pesquisa - Temático