Germination‚ duplication cycle and septum formation are altered by caffeine‚ caffeic acid and cinnamic acid in Aspergillus nidulans

Autor(es)

Yuvamoto‚ PD ; Said‚ S.

• Tipo de documento: Artigo Científico
• Fonte: MICROBIOLOGY; v. 76, n. 6, p. 735-738, 2007.

Resumo

Phytogenous Phenolic and benzene compounds have been described as being responsible for many biological activities including antifungal effects. The effect of caffeine and cinnamic and caffeic acids on a model fungus, Aspergillus nidulans, was investigated at its initial stage of germination. Conidia did not germinate in the presence of cinnamic acid (1 mM). Caffeine and caffeic acid exerted a negative effect on germination, on the nuclear duplication cycle and on first septum formation. The effects of caffeine were dose-dependent; effects of caffeic acid (1 mM) were more intense than those of caffeine (10 mM). (AU)

• Processo FAPESP: 02/11874-7 - Alteracoes no desenvolvimento celular e morfologia de aspergillus nidulans induzidas pela fonte de carbono: as vias de transducao de sinais.
• Beneficiário: Suraia Said
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 02/11875-3 - Efeito de inibidores da fosfolipase C (PLC) sobre a divisão nuclear e a septação em Aspergillus nidulans
• Beneficiário: Priscila Dorigao Yuvamoto
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica