Germination‚ duplication cycle and septum formation are altered by caffeine‚ caffeic acid and cinnamic acid in Aspergillus nidulans

Yuvamoto‚ PD; Said‚ S.

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Germination‚ duplication cycle and septum formation are altered by caffeine‚ caffeic acid and cinnamic acid in Aspergillus nidulans

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Author(s):	Yuvamoto‚ PD ; Said‚ S. Total Authors: 2
Document type:	Journal article
Source:	MICROBIOLOGY; v. 76, n. 6, p. 735-738, 2007.
Abstract
Phytogenous Phenolic and benzene compounds have been described as being responsible for many biological activities including antifungal effects. The effect of caffeine and cinnamic and caffeic acids on a model fungus, Aspergillus nidulans, was investigated at its initial stage of germination. Conidia did not germinate in the presence of cinnamic acid (1 mM). Caffeine and caffeic acid exerted a negative effect on germination, on the nuclear duplication cycle and on first septum formation. The effects of caffeine were dose-dependent; effects of caffeic acid (1 mM) were more intense than those of caffeine (10 mM). (AU)

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