Human coronavirus NL-63 infection in a Brazilian patient suspected of H1N1 2009 influenza infection: Description of a fatal case

Autor(es)

Cabeca, Tatiane K. ^[1] ; Bellei, Nancy ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo SP, Clin Virol Lab, Univ Fed Sao Paulo, Discipline Infectol, Dept Med, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Clinical Virology; v. 53, n. 1, p. 82-84, JAN 2012.
• Citações Web of Science: 13

Resumo

Human coronaviruses (HCoVs) cause upper respiratory tract and occasionally lower respiratory tract diseases. The recently described human coronavirus NL63 has not been well investigated among Brazilian patients. We reported the clinical course of an HCoV-NL63 infection in a hospitalised patient suspected of H1N1 2009 infection during the second pandemic wave of influenza activity. A 46-year-old female, health care worker with diabetes and presenting with influenza-like illness (ILI) was admitted to the hospital. During 9 days of influenza-like symptoms, the patient had diabetes decompensation, haemorrhagic pneumonia, rhabdomyolysis, respiratory and renal failure, pericarditis, and brain edema and died. HCoV-NL63 may be a causative agent of previously unexplained respiratory illnesses. Crown Copyright (C) 2011 Published by Elsevier B. V. All rights reserved. (AU)

• Processo FAPESP: 09/17307-6 - Infecção por Coronavirus humanos em populações distintas: aspectos clínicos e epidemiológicos
• Beneficiário: Nancy Cristina Junqueira Bellei
• Modalidade de apoio: Auxílio à Pesquisa - Regular