First detection of the equine herpesvirus 1 neuropathogenic variant in Brazil

Autor(es):Mostrar menos -

Mori, E. ^[1] ; Borges, A. S. ^[2] ; Delfiol, D. J. Z. ^[2] ; Oliveira Filho, J. P. ^[2] ; Goncalves, R. C. ^[2] ; Cagnini, D. Q. ^[2] ; Lara, M. C. C. S. H. ^[3] ; Cunha, E. M. S. ^[3] ; Villalobos, E. M. C. ^[3] ; Nassar, A. F. C. ^[3] ; Castro, A. M. M. G. ^[1] ; Brandao, P. E. ^[1] ; Richtzenhain, L. J. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo USP, Dept Prevent Vet Med & Anim Hlth, Fac Vet Med & Anim Sci FMVZ, BR-05508270 Sao Paulo - Brazil

^[2] Sao Paulo State Univ UNESP, Dept Vet Clin Sci, Fac Vet Med & Anim Sci FMVZ, BR-18618000 Botucatu, SP - Brazil

^[3] Inst Biol, Ctr Anim Hlth, BR-04014002 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES; v. 30, n. 3, p. 949-954, DEC 2011.
• Citações Web of Science: 6

Resumo

This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G(2254)/D-752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A(2254)/N-752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil. (AU)

• Processo FAPESP: 07/58861-0 - Caracterização sorológica e molecular da infecção viral em cavalos causada pelos herpesvírus equinos tipos 1 (EHV-1) e 4 (EHV-4)
• Beneficiário: Leonardo José Richtzenhain
• Modalidade de apoio: Auxílio à Pesquisa - Regular