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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

First detection of the equine herpesvirus 1 neuropathogenic variant in Brazil

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Author(s):
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Mori, E. [1] ; Borges, A. S. [2] ; Delfiol, D. J. Z. [2] ; Oliveira Filho, J. P. [2] ; Goncalves, R. C. [2] ; Cagnini, D. Q. [2] ; Lara, M. C. C. S. H. [3] ; Cunha, E. M. S. [3] ; Villalobos, E. M. C. [3] ; Nassar, A. F. C. [3] ; Castro, A. M. M. G. [1] ; Brandao, P. E. [1] ; Richtzenhain, L. J. [1]
Total Authors: 13
Affiliation:
[1] Univ Sao Paulo USP, Dept Prevent Vet Med & Anim Hlth, Fac Vet Med & Anim Sci FMVZ, BR-05508270 Sao Paulo - Brazil
[2] Sao Paulo State Univ UNESP, Dept Vet Clin Sci, Fac Vet Med & Anim Sci FMVZ, BR-18618000 Botucatu, SP - Brazil
[3] Inst Biol, Ctr Anim Hlth, BR-04014002 Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES; v. 30, n. 3, p. 949-954, DEC 2011.
Web of Science Citations: 6
Abstract

This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G(2254)/D-752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A(2254)/N-752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil. (AU)