Photoprotective Effects of Topical Formulations Containing a Combination of Ginkgo biloba and Green Tea Extracts

Autor(es)

Dal Belo, Susi Elaine ^[1] ; Gaspar, Lorena Rigo ^[1] ; Goncalves Maia Campos, Patricia Maria Berardo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Pharmaceut Sci, BR-14040903 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Phytotherapy Research; v. 25, n. 12, p. 1854-1860, DEC 2011.
• Citações Web of Science: 13

Resumo

The beneficial photoprotective effects of topical formulations containing combined extracts of Ginkgo biloba (GB) and green tea (GT) have not been investigated. The present study aims to assess the photoprotective effects of topical formulations containing GB and GT combined or not by applications on the dorsal skin of hairless mice prior to UVA/B irradiation. After 20 h, skin barrier damage (TEWL), erythema, histological alterations and sunburn cell formation were evaluated. The results showed that only extract supplemented formulations protected the skin against the UV-induced damage. Formulations containing GB provided total protection of the skin barrier function avoiding UV radiation damage such as TEWL and erythema and were more effective than those containing GT. However, it is suggested that formulations containing combined GB and GT may provide substantial photoprotective effects since different aspects of skin damage were influenced by each extract. Copyright (C) 2011 John Wiley \& Sons, Ltd. (AU)

• Processo FAPESP: 99/07259-0 - Desenvolvimento de formulacoes dermocosmeticas contendo filtros solares em associacao ou nao com vitaminas c ou e e de formulacoes contendo hidroxi acidos: avaliacao da estabilidade, dos seus efeitos..
• Beneficiário: Patrícia Maria Berardo Gonçalves Maia Campos
• Modalidade de apoio: Auxílio à Pesquisa - Regular