Parent psychopathology and offspring mental disorders: results from the WHO World Mental Health Surveys

Autor(es):Mostrar menos -

McLaughlin, Katie A. ^[1] ; Gadermann, Anne M. ^[2] ; Hwang, Irving ^[2] ; Sampson, Nancy A. ^[2] ; Al-Hamzawi, Ali ^[3] ; Andrade, Laura Helena ^[4] ; Angermeyer, Matthias C. ^[5] ; Benjet, Corina ^[6] ; Bromet, Evelyn J. ^[7] ; Bruffaerts, Ronny ^[8] ; Caldas-de-Almeida, Jose Miguel ^{[9, 10]} ; de Girolamo, Giovanni ^[11] ; de Graaf, Ron ^[12] ; Florescu, Silvia ^[13] ; Gureje, Oye ^[14] ; Maria Haro, Josep ^[15] ; Hinkov, Hristo Ruskov ^[16] ; Horiguchi, Itsuko ^[17] ; Hu, Chiyi ^{[18, 19]} ; Karam, Aimee Nasser ^{[20, 21]} ; Kovess-Masfety, Viviane ^{[22, 23]} ; Lee, Sing ^[24] ; Murphy, Samuel D. ^[25] ; Nizamie, S. Haque ^[26] ; Posada-Villa, Jose ^[27] ; Williams, David R. ^[28] ; Kessler, Ronald C. ^[2]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Harvard Univ, Sch Med, Childrens Hosp Boston, Div Gen Pediat, Boston, MA 02115 - USA

^[2] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 - USA

^[3] Al Qadisia Univ, Coll Med, Diwaniya Governorate - Iraq

^[4] Univ Sao Paulo, Sch Med, Inst Psychiat, Sect Psychiat Epidemiol LIM 23, Sao Paulo - Brazil

^[5] Ctr Publ Mental Hlth, Gosing Am Wagram - Austria

^[6] Natl Inst Psychiat Ramon de la Fuente, Div Epidemiol & Psychosocial Res, Mexico City, DF - Mexico

^[7] SUNY Stony Brook, Dept Psychiat, Stony Brook, NY 11794 - USA

^[8] Katholieke Univ Leuven, UPC, Louvain - Belgium

^[9] Univ Nova Lisboa, Chron Dis Res Ctr CEDOC, P-1200 Lisbon - Portugal

^[10] Univ Nova Lisboa, Dept Mental Hlth, Fac Ciencias Med, P-1200 Lisbon - Portugal

^[11] IRCCS Ctr San Giovanni Dio Fatebenefratelli Bresc, San Giovanni Rotondo - Italy

^[12] Netherlands Inst Mental Hlth & Addict, Utrecht - Netherlands

^[13] Natl Sch Publ Hlth Management & Profess Dev, Bucharest - Romania

^[14] Univ Coll Ibadan Hosp, Ibadan - Nigeria

^[15] Univ Barcelona, CIBERSAM, Barcelona - Spain

^[16] Natl Ctr Publ Hlth Protect, Sofia - Bulgaria

^[17] Juntendo Univ, Dept Publ Hlth, Grad Sch Med, Tokyo - Japan

^[18] Shenzhen Inst Mental Hlth, Shenzhen - Peoples R China

^[19] Shenzhen Kangning Hosp, Shenzhen - Peoples R China

^[20] IDRAAC, Beirut - Lebanon

^[21] Balamand Univ, Sch Med, Dept Psychiat & Clin Psychol, St George Hosp Univ Med Ctr, Beirut - Lebanon

^[22] Univ Paris 05, EA 4069, Paris - France

^[23] EHESP Sch Publ Hlth, Dept Epidemiol, Paris - France

^[24] Chinese Univ Hong Kong, Hong Kong, Hong Kong - Peoples R China

^[25] Univ Ulster, Sch Psychol, Coleraine BT52 1SA, Londonderry - North Ireland

^[26] Cent Inst Psychiat, Ranchi, Jharkhand - India

^[27] Inst Colombiano Sistema Nervioso, Bogota - Colombia

^[28] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 - USA

• Tipo de documento: Artigo Científico
• Fonte: BRITISH JOURNAL OF PSYCHIATRY; v. 200, n. 4, p. 290-299, APR 2012.
• Citações Web of Science: 80

Resumo

Background Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity. Aims To examine the associations of parent with respondent disorders. Method Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews. Results Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle-than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders. Conclusions Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders. (AU)

• Processo FAPESP: 03/00204-3 - Estudo epidemiológico dos transtornos psiquiátricos na região metropolitana de São Paulo: prevalências, fatores de risco e sobrecarga social e econômica
• Beneficiário: Laura Helena Silveira Guerra de Andrade
• Modalidade de apoio: Auxílio à Pesquisa - Temático